[HTML][HTML] Role of microRNAs in translation regulation and cancer
S Oliveto, M Mancino, N Manfrini… - World journal of biological …, 2017 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are pervasively expressed and regulate most biological functions.
They function by modulating transcriptional and translational programs and therefore they …
They function by modulating transcriptional and translational programs and therefore they …
Mechanisms of miRNA‐mediated gene regulation from common downregulation to mRNA‐specific upregulation
A Valinezhad Orang, R Safaralizadeh… - … journal of genomics, 2014 - Wiley Online Library
Discovered in 1993, micoRNAs (miRNAs) are now recognized as one of the major
regulatory gene families in eukaryotes. To date, 24521 microRNAs have been discovered …
regulatory gene families in eukaryotes. To date, 24521 microRNAs have been discovered …
Regulation of mRNA translation and stability by microRNAs
MR Fabian, N Sonenberg… - Annual review of …, 2010 - annualreviews.org
MicroRNAs (miRNAs) are small noncoding RNAs that extensively regulate gene expression
in animals, plants, and protozoa. miRNAs function posttranscriptionally by usually base …
in animals, plants, and protozoa. miRNAs function posttranscriptionally by usually base …
[HTML][HTML] MicroRNAs: target recognition and regulatory functions
DP Bartel - cell, 2009 - cell.com
MicroRNAs (miRNAs) are endogenous∼ 23 nt RNAs that play important gene-regulatory
roles in animals and plants by pairing to the mRNAs of protein-coding genes to direct their …
roles in animals and plants by pairing to the mRNAs of protein-coding genes to direct their …
Posttranscriptional upregulation by microRNAs
S Vasudevan - Wiley Interdisciplinary Reviews: RNA, 2012 - Wiley Online Library
MicroRNAs are small non‐coding RNA guide molecules that regulate gene expression via
association with effector complexes and sequence‐specific recognition of target sites on …
association with effector complexes and sequence‐specific recognition of target sites on …
Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity
In animals, P-bodies or GW-bodies appear to cause the congregation of proteins involved in
microRNA (miRNA)-mediated post-transcriptional silencing. The localization of P-bodies …
microRNA (miRNA)-mediated post-transcriptional silencing. The localization of P-bodies …
Stabilization of hepatitis C virus RNA by an Ago2–miR-122 complex
T Shimakami, D Yamane, RK Jangra… - Proceedings of the …, 2012 - National Acad Sciences
MicroRNAs (miRNAs) are small noncoding RNAs that regulate eukaryotic gene expression
by binding to regions of imperfect complementarity in mRNAs, typically in the 3′ UTR …
by binding to regions of imperfect complementarity in mRNAs, typically in the 3′ UTR …
Elevated expression of microRNAs 155, 203, 210 and 222 in pancreatic tumors is associated with poorer survival
T Greither, LF Grochola, A Udelnow… - … journal of cancer, 2010 - Wiley Online Library
Pancreatic cancer is the eighth most common cancer and has an overall 5‐year survival rate
lower than 10%. Because of their ability to regulate gene expression, microRNAs can act as …
lower than 10%. Because of their ability to regulate gene expression, microRNAs can act as …
microRNAs: Master regulators as potential therapeutics in cancer
M Garofalo, CM Croce - Annual review of pharmacology and …, 2011 - annualreviews.org
It has been demonstrated that all the known processes involved in cancer, including
apoptosis, proliferation, survival, and metastasis, are regulated by small regulatory …
apoptosis, proliferation, survival, and metastasis, are regulated by small regulatory …
Understanding microRNAs in neurodegeneration
Interest in the functions of microRNAs (miRNAs) in the nervous system has recently
expanded to include their roles in neurodegeneration. Investigations have begun to reveal …
expanded to include their roles in neurodegeneration. Investigations have begun to reveal …