[HTML][HTML] Genetics, pathophysiology, diagnosis, treatment, management, and prevention of migraine

J Khan, LI Al Asoom, A Al Sunni, N Rafique… - Biomedicine & …, 2021 - Elsevier
Migraine is a neurological ailment that is characterized by severe throbbing unilateral
headache and associated with nausea, photophobia, phonophobia and vomiting. A full and …

Genetics of migraine: where are we now?

L Grangeon, KS Lange, M Waliszewska-Prosół… - The Journal of …, 2023 - Springer
Migraine is a complex brain disorder explained by the interaction of genetic and
environmental factors. In monogenic migraines, including familial hemiplegic migraine and …

Human and mouse trigeminal ganglia cell atlas implicates multiple cell types in migraine

L Yang, M Xu, SA Bhuiyan, J Li, J Zhao, RJ Cohrs… - Neuron, 2022 - cell.com
Sensitization of trigeminal ganglion neurons contributes to primary headache disorders such
as migraine, but the specific neuronal and non-neuronal trigeminal subtypes that are …

Structural and functional brain changes in migraine

S Ashina, E Bentivegna, P Martelletti… - Pain and therapy, 2021 - Springer
Migraine is a prevalent primary headache disorder and is usually considered as benign.
However, structural and functional changes in the brain of individuals with migraine have …

Diagnostic and therapeutic aspects of hemiplegic migraine

V Di Stefano, MG Rispoli, N Pellegrino… - Journal of Neurology …, 2020 - jnnp.bmj.com
Hemiplegic migraine (HM) is a clinically and genetically heterogeneous condition with
attacks of headache and motor weakness which may be associated with impaired …

[PDF][PDF] Navigating the Neurobiology of Migraine: from pathways to potential therapies

M Tanaka, B Tuka, L Vécsei - Cells, 2024 - mdpi.com
Migraine is a debilitating neurological disorder characterized by recurring episodes of
throbbing headaches that are frequently accompanied by sensory disturbances, nausea …

Medication overuse and drug addiction: a narrative review from addiction perspective

TT Takahashi, R Ornello, G Quatrosi, A Torrente… - The journal of headache …, 2021 - Springer
Chronic headache is particularly prevalent in migraineurs and it can progress to a condition
known as medication overuse headache (MOH). MOH is a secondary headache caused by …

[HTML][HTML] Towards precision medicine in migraine: Recent therapeutic advances and potential biomarkers to understand heterogeneity and treatment response

G Juhasz, K Gecse, D Baksa - Pharmacology & Therapeutics, 2023 - Elsevier
After 35 years since the introduction of the International Classification of Headache
Disorders (ICHD), we are living in the era of the second great revolution in migraine …

Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools

S Bahrami, G Hindley, BS Winsvold, KS O'Connell… - Brain, 2022 - academic.oup.com
Migraine is three times more prevalent in people with bipolar disorder or depression. The
relationship between schizophrenia and migraine is less certain although glutamatergic and …

Epigenetic connection of the calcitonin gene-related peptide and its potential in migraine

M Fila, A Sobczuk, E Pawlowska, J Blasiak - International journal of …, 2022 - mdpi.com
The calcitonin gene-related peptide (CGRP) is implicated in the pathogenesis of several
pain-related syndromes, including migraine. Targeting CGRP and its receptor by their …