The NF-κB signaling pathway is a key regulator of CRC cell proliferation, apoptosis,
angiogenesis, inflammation, metastasis, and drug resistance. Over-activation of the NF-κB …

Gastric cancer is a leading cause of cancer death worldwide. Diet, obesity, smoking and
chronic infections, especially with Helicobacter pylori, contribute to stomach cancer …

Abstract Development of drug resistance to standard chemotherapy is a common
phenomenon that leads to poor prognosis in patients. Thus, novel agents that can attenuate …

Chemoresistance remains a major problem in the treatment of gastric cancer patients.
Hence, novel pharmacological agents that can overcome drug resistance are urgently …

The NF-kB1 gene belongs to the family of transcription factors that are involved in the
regulation of a wide range of biological reactions. It has been established that NF-kB1 plays …

Nuclear factor kappa B (NF-κB) has an established role in the regulation of innate immunity
and inflammation. NF-κB is also involved in critical mechanisms connecting inflammation …

Multidrug resistance (MDR), of the innate and acquired types, is one of major problems in
treating tumor diseases with a good chance of success. In this review, we examine the key …

Nuclear factor-κB (NF-κB) is one of the most important transcription factors; it has a key role
in inflammatory and immune responses, cell adhesion, developmental signals, and anti …

Objectives: Exportin 1 (XPO1), a nuclear exporter protein, has been gaining recognition in
cancer progression and treatment. This study aimed to evaluate the association between the …

Paclitaxel has been used widely to treat breast cancer and other types of cancer. However,
resistance is a major cause of failure for treatment and results in cancer progression. The …