Bat-borne virus diversity, spillover and emergence

M Letko, SN Seifert, KJ Olival, RK Plowright… - Nature Reviews …, 2020 - nature.com
Most viral pathogens in humans have animal origins and arose through cross-species
transmission. Over the past 50 years, several viruses, including Ebola virus, Marburg virus …

One Health, emerging infectious diseases and wildlife: two decades of progress?

AA Cunningham, P Daszak… - … Transactions of the …, 2017 - royalsocietypublishing.org
Infectious diseases affect people, domestic animals and wildlife alike, with many pathogens
being able to infect multiple species. Fifty years ago, following the wide-scale manufacture …

The pathogenesis of Ebola virus disease

L Baseler, DS Chertow, KM Johnson… - Annual Review of …, 2017 - annualreviews.org
For almost 50 years, ebolaviruses and related filoviruses have been repeatedly reemerging
across the vast equatorial belt of the African continent to cause epidemics of highly fatal …

Pathogenicity and virulence of Marburg virus

MH Abir, T Rahman, A Das, SN Etu, IH Nafiz, A Rakib… - Virulence, 2022 - Taylor & Francis
Marburg virus (MARV) has been a major concern since 1967, with two major outbreaks
occurring in 1998 and 2004. Infection from MARV results in severe hemorrhagic fever …

The Egyptian rousette genome reveals unexpected features of bat antiviral immunity

SS Pavlovich, SP Lovett, G Koroleva, JC Guito… - Cell, 2018 - cell.com
Bats harbor many viruses asymptomatically, including several notorious for causing extreme
virulence in humans. To identify differences between antiviral mechanisms in humans and …

Immune system modulation and viral persistence in bats: understanding viral spillover

S Subudhi, N Rapin, V Misra - Viruses, 2019 - mdpi.com
Bats harbor a myriad of viruses and some of these viruses may have spilled over to other
species including humans. Spillover events are rare and several factors must align to create …

Transmission or within-host dynamics driving pulses of zoonotic viruses in reservoir–host populations

RK Plowright, AJ Peel, DG Streicker… - PLoS Neglected …, 2016 - journals.plos.org
Progress in combatting zoonoses that emerge from wildlife is often constrained by limited
knowledge of the biology of pathogens within reservoir hosts. We focus on the host …

[HTML][HTML] Asymptomatic infection of Marburg virus reservoir bats is explained by a strategy of immunoprotective disease tolerance

JC Guito, JB Prescott, CE Arnold, BR Amman… - Current biology, 2021 - cell.com
Marburg virus (MARV) is among the most virulent pathogens of primates, including humans.
Contributors to severe MARV disease include immune response suppression and …

Going to bat (s) for studies of disease tolerance

JN Mandl, C Schneider, DS Schneider… - Frontiers in …, 2018 - frontiersin.org
A majority of viruses that have caused recent epidemics with high lethality rates in people,
are zoonoses originating from wildlife. Among them are filoviruses (eg, Marburg, Ebola) …

Assessment of listing and categorisation of animal diseases within the framework of the Animal Health Law (Regulation (EU) No 2016/429): bluetongue

EFSA Panel on Animal Health and Welfare … - Efsa …, 2017 - Wiley Online Library
A specific concept of strain was developed in order to classify the BTV serotypes ever
reported in Europe based on their properties of animal health impact: the genotype …