Neuroinflammation: a potential risk for dementia
Dementia is a neurodegenerative condition that is considered a major factor contributing to
cognitive decline that reduces independent function. Pathophysiological pathways are not …
cognitive decline that reduces independent function. Pathophysiological pathways are not …
Role of Natural Compounds and Target Enzymes in the Treatment of Alzheimer's Disease
S Wang, X Kong, Z Chen, G Wang, J Zhang, J Wang - Molecules, 2022 - mdpi.com
Alzheimer's disease (AD) is a progressive neurological condition. The rising prevalence of
AD necessitates the rapid development of efficient therapy options. Despite substantial …
AD necessitates the rapid development of efficient therapy options. Despite substantial …
Molecular docking and dynamics simulation approach of Camellia sinensis leaf extract derived compounds as potential cholinesterase inhibitors
The tea plant (Camellia sinensis) belongs to the family Theaceae and contains many
phytochemicals that are effective against various diseases, including neurodegenerative …
phytochemicals that are effective against various diseases, including neurodegenerative …
Natural bioactive as a potential therapeutic approach for the management of cyclophosphamide-induced cardiotoxicity
Cyclophosphamide (CP) is an extensively used anticancer drug, but its cardiotoxic
manifestation is a major concern for its widespread clinical use. The observed cardiotoxic …
manifestation is a major concern for its widespread clinical use. The observed cardiotoxic …
COVID-19 and cardiovascular complications: an update from the underlying mechanism to consequences and possible clinical intervention
Introduction: The novel coronavirus has caused significant mortality worldwide and is
primarily associated with severe acute respiratory distress syndrome (ARDS). Apart from …
primarily associated with severe acute respiratory distress syndrome (ARDS). Apart from …
Development, optimization, and evaluation of Empagliflozin nanoemulsion for the management of neuroinflammation associated Alzheimer's disease
NA Alhakamy, EA Aljehani, AB Abdel-Naim… - Journal of Drug Delivery …, 2024 - Elsevier
Alzheimer's disease (AD) is one of the most pervasive and progressive neurodegenerative
disorders. Recently, empagliflozin (EMPA) has been reported as a potent anti-inflammatory …
disorders. Recently, empagliflozin (EMPA) has been reported as a potent anti-inflammatory …
Synthetic and Natural Bioactive Molecules in Balancing the Crosstalk among Common Signaling Pathways in Alzheimer's Disease: Understanding the Neurotoxic …
The structure and function of the brain greatly rely on different signaling pathways. The wide
variety of biological processes, including neurogenesis, axonal remodeling, the …
variety of biological processes, including neurogenesis, axonal remodeling, the …
Role of multi-targeted bioactive natural molecules and their derivatives in the treatment of Alzheimer's disease: an insight into structure-activity relationship
Alzheimer's disease (AD) is a complex neurodegenerative disorder involving cognitive
dysfunction like short-term memory and behavioral changes as the disease progresses due …
dysfunction like short-term memory and behavioral changes as the disease progresses due …
Mechanisms involved in microglial-interceded Alzheimer's disease and nanocarrier-based treatment approaches
Alzheimer's disease (AD) is a common neurodegenerative disorder accountable for
dementia and cognitive dysfunction. The etiology of AD is complex and multifactorial in …
dementia and cognitive dysfunction. The etiology of AD is complex and multifactorial in …
Pathogenic mechanisms and therapeutic promise of phytochemicals and nanocarriers based drug delivery against radiotherapy-induced neurotoxic manifestations
Radiotherapy is one of the extensively used therapeutic modalities in glioblastoma and
other types of cancers. Radiotherapy is either used as a first-line approach or combined with …
other types of cancers. Radiotherapy is either used as a first-line approach or combined with …