NOD-like receptor family pyrin domain containing 3 (NLRP3) is an intracellular receptor that
senses foreign pathogens and endogenous danger signals. It assembles with apoptosis …

Inflammation is a pivotal response to a variety of stimuli, and inflammatory molecules such
as cytokines have central roles in the pathogenesis of various diseases, including bone and …

Inflammasomes are intracellular multiprotein signaling platforms that initiate inflammatory
responses in response to pathogens and cellular damage. Active inflammasomes induce …

Control of excessive mitochondrial oxidative stress could provide new targets for both
preventive and therapeutic interventions in the treatment of chronic inflammation or any …

Inflammasomes are a multi-protein platform forming a part of the innate immune system.
Inflammasomes are at standby status and can be activated when needed. Inflammasome …

Inflammasome is a cytoplasmic multiprotein complex that facilitates the clearance of
exogenous microorganisms or the recognition of endogenous danger signals, which is …

Osteoarthritis is age-related and the most common form of arthritis. The main characteristics
of the disease are progressive loss of cartilage and secondary synovial inflammation, which …

Ethnopharmacological relevance It has been widely reported that various anti-rheumatic
traditional Chinese medicines (TCMs) ameliorate rheumatoid arthritis (RA) and osteoarthritis …

Inflammasomes are multi‐protein complexes that assemble within the cytoplasm of
mammalian cells in response to pathogen‐associated molecular patterns (PAMPs) or …

Gout, the most common inflammatory arthritis, is the result of hyperuricemia and
inflammation induced by monosodium urate (MSU) crystal deposition. However, most …