The fundamental roles that peptides and proteins play in today's biology makes it almost
indisputable that peptides were key players in the origin of life. Insofar as it is appropriate to …

The present review offers an overview of nonclassical (eg, with no pre-or in situ activation of
a carboxylic acid partner) approaches for the construction of amide bonds. The review aims …

Following the discovery of nitric oxide (NO) and carbon monoxide (CO), hydrogen sulfide
(H2S) has been identified as the third gasotransmitter in humans. Increasing evidence have …

Accessible drug modalities have continued to increase in number in recent years. Peptides
play a central role as pharmaceuticals and biomaterials in these new drug modalities …

Conspectus Reactive sulfur species (RSS) play regulatory roles in many physiological and
pathological processes. Since the discovery of hydrogen sulfide (H2S) as a nitric oxide (NO) …

Amide bonds are one of the underpinning linkages in all living systems and are fundamental
within drug discovery. Current methods towards their synthesis frequently rely on the use of …

Recent studies suggest that inorganic hydrogen polysulfides (H2Sn, n≥ 2) play important
regulatory roles in redox biology. Modulation of their cellular levels could have potential …

Glycosylation is a major modification of secreted and cell surface proteins, and the resultant
glycans show considerable heterogeneity in their structures. To understand the biological …

Reactive sulfur species (RSS) are biologically important molecules. Among them, H2S,
hydrogen polysulfides (H2Sn, n> 1), persulfides (RSSH), and HSNO are believed to play …

A remarkable visible-light-promoted photoredox catalytic methodology involved with amines
and eco-friendly potassium thioacids for amide formation was uncovered. This approach can …