Chemokines–chemotactic cytokines–are small secreted proteins that attract and activate
immune and non-immune cells in vitro and in vivo. It has been suggested that chemokines …

Chemotactic cytokines (chemokines) have been traditionally defined as small (10–14kDa)
secreted leukocyte chemoattractants. However, chemokines and their cognate receptors are …

Chemokines are not only found in the immune system or expressed in inflammatory
conditions: they are constitutively present in the brain in both glial cells and neurons …

The chemokine CXCL12/stromal cell-derived factor 1 alpha has first been described in the
immune system where it functions include chemotaxis for lymphocytes and macrophages …

Psychiatric disorders are highly prevalent and disabling conditions of increasing public
health relevance. Much recent research has focused on the role of cytokines in the …

In the CNS, chemokines and chemokine receptors are involved in pleiotropic physiological
and pathological activities. Several evidences demonstrated that chemokine signaling in the …

Epilepsy has been considered mainly a neuronal disease, without much attention to non-
neuronal cells. In recent years growing evidence suggest that astrocytes, microglia, blood …

Chemokines are not only mediators of the immune system and expressed in inflammatory
situations. They are also constitutively expressed in the brain in both glial cells and neurons …

Whereas chemokines are well known for their ability to induce cell migration, only recently it
became evident that chemokines also control a variety of other cell functions and are …

Abstract Background Mesenchymal stem cells (MSCs) are pluripotent stem cells derived
from bone marrow with secretory functions of various neurotrophic factors. Stromal cell …