APT‐weighted MRI: techniques, current neuro applications, and challenging issues

J Zhou, HY Heo, L Knutsson… - Journal of Magnetic …, 2019 - Wiley Online Library
Amide proton transfer‐weighted (APTw) imaging is a molecular MRI technique that
generates image contrast based predominantly on the amide protons in mobile cellular …

Applications of chemical exchange saturation transfer magnetic resonance imaging in identifying genetic markers in gliomas

S Jiang, Z Wen, SS Ahn, K Cai, D Paech… - NMR in …, 2023 - Wiley Online Library
Chemical exchange saturation transfer (CEST) imaging is an important molecular magnetic
resonance imaging technique that can image numerous low‐concentration biomolecules …

Noninvasive IDH1 mutation estimation based on a quantitative radiomics approach for grade II glioma

J Yu, Z Shi, Y Lian, Z Li, T Liu, Y Gao, Y Wang… - European …, 2017 - Springer
Objective The status of isocitrate dehydrogenase 1 (IDH1) is highly correlated with the
development, treatment and prognosis of glioma. We explored a noninvasive method to …

Assessing the predictability of IDH mutation and MGMT methylation status in glioma patients using relaxation-compensated multipool CEST MRI at 7.0 T

D Paech, J Windschuh, J Oberhollenzer… - Neuro …, 2018 - academic.oup.com
Background Early identification of prognostic superior characteristics in glioma patients such
as isocitrate dehydrogenase (IDH) mutation and O6-methylguanine-DNA-methyltransferase …

[HTML][HTML] Chemical exchange saturation transfer MRI serves as predictor of early progression in glioblastoma patients

S Regnery, S Adeberg, C Dreher, J Oberhollenzer… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Chemical exchange saturation transfer MRI serves as predictor of early progression in
glioblastoma patients - PMC Back to Top Skip to main content NIH NLM Logo Access keys …

Diagnostic performance of gliomas grading and IDH status decoding A comparison between 3D amide proton transfer APT and four diffusion‐weighted MRI models

H Guo, J Liu, JJ Hu, HT Zhang, W Zhao… - Journal of Magnetic …, 2022 - Wiley Online Library
Background The focus of neuro‐oncology research has changed from histopathologic
grading to molecular characteristics, and medical imaging routinely follows this change …

A comparative study of the value of amide proton transfer-weighted imaging and diffusion kurtosis imaging in the diagnosis and evaluation of breast cancer

N Meng, X Wang, J Sun, D Han, Y Bai, W Wei… - European …, 2021 - Springer
Objectives To compare the value of amide proton transfer-weighted imaging (APTWI) and
diffusion kurtosis imaging (DKI) in differentiating benign and malignant breast lesions and …

Validation of the presence of fast exchanging amine CEST effect at low saturation powers and its influence on the quantification of APT

C Sun, Y Zhao, Z Zu - Magnetic resonance in medicine, 2023 - Wiley Online Library
Purpose Accurately quantifying the amide proton transfer (APT) effect and the underlying
exchange parameters is crucial for its applications, but previous studies have reported …

Diagnostic performance between MR amide proton transfer (APT) and diffusion kurtosis imaging (DKI) in glioma grading and IDH mutation status prediction at 3 T

Z Xu, C Ke, J Liu, S Xu, L Han, Y Yang, L Qian… - European journal of …, 2021 - Elsevier
Purpose Accurate glioma grading and IDH mutation status prediction are critically essential
for individualized preoperative treatment decisions. This study aims to compare the …

[HTML][HTML] Fast and equilibrium CEST imaging of brain tumor patients at 3T

Y Wu, Z Liu, Q Yang, L Zou, F Zhang, L Qian, X Liu… - NeuroImage: Clinical, 2022 - Elsevier
Chemical exchange saturation transfer (CEST) MRI, versatile for detecting endogenous
mobile proteins and tissue pH, has proved valuable in tumor imaging. However, CEST MRI …