The enhancement of wound healing has been a goal of medical practitioners for thousands
of years. The development of chronic, non-healing wounds is a persistent medical problem …

Wound healing is an intricate process that requires complex coordination between many cell
types and an appropriate extracellular microenvironment. Chronic wounds often suffer from …

Nowadays, there has been an increase in the number of people with chronic wounds, which
has resulted in serious health problems worldwide. The rate-limiting stage of chronic wound …

The blood vessel system is essential for skin homeostasis and regeneration. While the
heterogeneity of vascular endothelial cells has been emergingly revealed, whether a …

Diabetes mellitus (DM) is a chronic systemic disease with increasing prevalence globally.
An important aspect of diabetic pathogenesis is cellular crosstalk and information exchange …

Fluid shear stresses are potent regulators of vascular homeostasis and powerful
determinants of vascular disease progression. The glycocalyx is a layer of …

The combination of pharmaceutical technologies can be a wise choice for developing
innovative therapeutic strategies. The association of nanocarriers and gels provides new …

Non-healing ulcers are a common consequence of long-term diabetes and severe
peripheral vascular disease. These non-healing wounds are a major source of morbidity in …

Peripheral vascular disease (PVD) is one of the most prevalent vascular diseases in the US
afflicting an estimated 8 million people. Obstruction of peripheral arteries leads to insufficient …

Chronic wounds caused by infections, diabetes, and radiation exposures are becoming a
worldwide growing medical burden. Recent progress highlighted the physical signals …