Vascular endothelial cells form the inner layer of blood vessels where they have a key role
in the development and maintenance of the functional circulatory system and provide …

Blood flow produces mechanical frictional forces, parallel to the blood flow exerted on the
endothelial wall of the vessel, the so-called wall shear stress (WSS). WSS sensing is …

Vascular endothelial cell (EC) function depends on appropriate organ-specific molecular
and cellular specializations. To explore genomic mechanisms that control this specialization …

The endothelium is the cell monolayer that lines the interior of the blood vessels separating
the vessel lumen where blood circulates, from the surrounding tissues. During embryonic …

The formation of arteries is thought to occur by the induction of a highly conserved arterial
genetic programme in a subset of vessels that will later experience an increase in …

Located in the innermost layer of the vasculature and directly interacting with blood flow,
endothelium integrates various biochemical and biomechanical signals to maintain barrier …

The availability of viral entry factors is a prerequisite for the cross-species transmission of
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Large-scale single-cell …

Collateral arteries are an uncommon vessel subtype that can provide alternate blood flow to
preserve tissue following vascular occlusion. Some patients with heart disease develop …

Systemic and pulmonary circulations constitute a complex organ that serves multiple
important biological functions. Consequently, any pathological processing affecting the …

Aims Coronary vasculature formation is a critical event during cardiac development,
essential for heart function throughout perinatal and adult life. However, current …