[HTML][HTML] Towards the functional high-resolution coordination chemistry of blood plasma human serum albumin

S Al-Harthi, JI Lachowicz, ME Nowakowski… - Journal of inorganic …, 2019 - Elsevier
Human serum albumin (HSA) is a monomeric, globular, multi-carrier and the most abundant
protein in the blood. HSA displays multiple ligand binding sites with extraordinary binding …

Palladium complexes: new candidates for anti-cancer drugs

EZ Jahromi, A Divsalar, AA Saboury… - Journal of the Iranian …, 2016 - Springer
Platinum complexes which are most studied metal complexes due to their importance as
adjuvant therapy of cancers aiming to induce tumor-cell-death. Some of the platinum-based …

Chlorogenic acid modulates autophagy by inhibiting the activity of ALKBH5 demethylase, thereby ameliorating hepatic steatosis

F Meng, C Song, J Liu, F Chen, YH Zhu… - Journal of Agricultural …, 2023 - ACS Publications
Chlorogenic acid (CGA) is a naturally occurring plant component with the purpose of
alleviating hepatic lipid deposition biological activities. However, the molecular mechanism …

Analysis of the structure and dynamics of human serum albumin

TRC Guizado - Journal of molecular modeling, 2014 - Springer
Human serum albumin (HSA) is a biologically relevant protein that binds a variety of drugs
and other small molecules. No less than 50 structures are deposited in the RCSB Protein …

Aromatic amine N-oxide organometallic compounds: searching for prospective agents against infectious diseases

ER Arce, MF Mosquillo, L Pérez-Díaz… - Dalton …, 2015 - pubs.rsc.org
In search of prospective agents against infectious diseases, 1, 1′-bis (diphenylphosphino)
ferrocene pyridine-2-thiolato-1-oxide M (II) hexafluorophosphate compounds [M …

Biological evaluation of a new synthesized Pt (II) complex by cytotoxic and spectroscopic studies

A Divsalar, M Razmi, AA Saboury… - Cell biochemistry and …, 2015 - Springer
In this study, the interaction of β-casein (β-CN) with a new synthesized Pt (II) complex
(bipyridin morpholin dithiocarbamate Pt (II) nitrate), as an anticancer compound, was …

Characterization and side effect analysis of a newly designed nanoemulsion targeting human serum albumin for drug delivery

A Divsalar, AA Saboury, M Nabiuni, Z Zare… - Colloids and Surfaces B …, 2012 - Elsevier
Human serum albumin (HSA), the most abundant protein in plasma, plays an important role
in the transportation of metabolic and exogenous compounds, particularly drugs. However, it …

Shear-induced aggregation of amyloid β (1–40) in a parallel plate geometry

LG Sharma, LM Pandey - Journal of Biomolecular Structure and …, 2021 - Taylor & Francis
Protein aggregation is induced by various environmental or external factors and associated
with various neurodegenerative diseases. Among various external factors, shear stress is …

Preclinical Pharmacokinetics and Biodistribution of Anticancer Dinuclear Palladium(II)-Spermine Complex (Pd2Spm) in Mice

M Vojtek, S Goncalves-Monteiro, E Pinto… - Pharmaceuticals, 2021 - mdpi.com
Palladium-based compounds are regarded as potential analogs to platinum anticancer
drugs with improved properties. The present study assessed the pharmacokinetics and …

Novel seleno-hydantoin palladium (II) complex-antimigratory, cytotoxic and prooxidative potential on human colon HCT-116 and breast MDA-MB-231 cancer cells

M Živanovic, J Kosaric, B Šmit, D Šeklić, R Pavlovic… - 2017 - scidar.kg.ac.rs
Selenium and palladium containing compounds separately exert multifunctional effects on
cells. While selenium containing compounds usually exert antioxidative properties …