Drosophila suzukii (Diptera: Drosophilidae): A Decade of Research Towards a Sustainable Integrated Pest Management Program
G Tait, S Mermer, D Stockton, J Lee… - Journal of Economic …, 2021 - academic.oup.com
Abstract Drosophila suzukii (Matsumura)(Diptera: Drosophilidae) also known as spotted-
wing drosophila (SWD), is a pest native to Southeast Asia. In the last few decades, the pest …
wing drosophila (SWD), is a pest native to Southeast Asia. In the last few decades, the pest …
Gene drives gaining speed
E Bier - Nature Reviews Genetics, 2022 - nature.com
Gene drives are selfish genetic elements that are transmitted to progeny at super-Mendelian
(> 50%) frequencies. Recently developed CRISPR–Cas9-based gene-drive systems are …
(> 50%) frequencies. Recently developed CRISPR–Cas9-based gene-drive systems are …
Combating mosquito-borne diseases using genetic control technologies
Mosquito-borne diseases, such as dengue and malaria, pose significant global health
burdens. Unfortunately, current control methods based on insecticides and environmental …
burdens. Unfortunately, current control methods based on insecticides and environmental …
Efficient population modification gene-drive rescue system in the malaria mosquito Anopheles stephensi
Abstract Cas9/gRNA-mediated gene-drive systems have advanced development of genetic
technologies for controlling vector-borne pathogen transmission. These technologies …
technologies for controlling vector-borne pathogen transmission. These technologies …
Development of a confinable gene drive system in the human disease vector Aedes aegypti
Aedes aegypti is the principal mosquito vector for many arboviruses that increasingly infect
millions of people every year. With an escalating burden of infections and the relative failure …
millions of people every year. With an escalating burden of infections and the relative failure …
Regulating the expression of gene drives is key to increasing their invasive potential and the mitigation of resistance
Homing-based gene drives use a germline source of nuclease to copy themselves at
specific target sites in a genome and bias their inheritance. Such gene drives can be …
specific target sites in a genome and bias their inheritance. Such gene drives can be …
Core commitments for field trials of gene drive organisms
Gene drive organisms (GDOs), whose genomes have been genetically engineered to
spread a desired allele through a population, have the potential to transform the way …
spread a desired allele through a population, have the potential to transform the way …
Symbionts and gene drive: two strategies to combat vector-borne disease
Mosquitoes bring global health problems by transmitting parasites and viruses such as
malaria and dengue. Unfortunately, current insecticide-based control strategies are only …
malaria and dengue. Unfortunately, current insecticide-based control strategies are only …
A CRISPR homing gene drive targeting a haplolethal gene removes resistance alleles and successfully spreads through a cage population
Engineered gene drives are being explored as a new strategy in the fight against vector-
borne diseases due to their potential for rapidly spreading genetic modifications through a …
borne diseases due to their potential for rapidly spreading genetic modifications through a …
A toxin-antidote CRISPR gene drive system for regional population modification
Engineered gene drives based on a homing mechanism could rapidly spread genetic
alterations through a population. However, such drives face a major obstacle in the form of …
alterations through a population. However, such drives face a major obstacle in the form of …