Four weeks of near-normalisation of blood glucose improves the insulin response to glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in …

PV Højberg, T Vilsbøll, R Rabøl, FK Knop, M Bache… - Diabetologia, 2009 - Springer
Objective The incretin effect is attenuated in patients with type 2 diabetes mellitus, partly as a
result of impaired beta cell responsiveness to glucose-dependent insulinotropic polypeptide …

Hyperglycemia acutely lowers the postprandial excursions of glucagon-like peptide-1 and gastric inhibitory polypeptide in humans

K Vollmer, H Gardiwal, BA Menge… - The Journal of …, 2009 - academic.oup.com
Introduction: Impaired secretion of glucagon-like peptide 1 (GLP-1) has been suggested to
contribute to the deficient incretin effect in patients with type 2 diabetes. It is unclear whether …

Comment on: Knop et al. (2007) Reduced Incretin Effect in Type 2 Diabetes: Cause or Consequence of the Diabetic State? Diabetes 56:1951–1959

SP Choukem, JF Gautier - Diabetes, 2008 - Am Diabetes Assoc
In the excellent article by Knop et al.(1), the authors use an interesting design to show that
the decreased incretin effect observed in patients with type 2 diabetes is a consequence of …

Einfluss einer Hyperglykämie auf die Magenentleerung sowie die Freisetzung von Glukagon like Peptide-1 und Gastric Inhibitory Polypeptide

H Gardiwal - 2015 - hss-opus.ub.ruhr-uni-bochum.de
Die Inkretinhormone GLP-1 und GIP vermitteln ca. 60% der postprandialen Insulin-Antwort
bei gesunden Menschen. Bei Patienten mit Typ 2 Diabetes ist dieser Inkretin-Effekt deutlich …