Inflammation context in Alzheimer's disease, a relationship intricate to define

C Novoa, P Salazar, P Cisternas, C Gherardelli… - Biological Research, 2022 - Springer
Abstract Alzheimer's disease (AD), the most common form of dementia, is characterized by
the accumulation of amyloid β (Aβ) and hyperphosphorylated tau protein aggregates …

Hypoxia and HIF signaling: one axis with divergent effects

C Corrado, S Fontana - International Journal of Molecular Sciences, 2020 - mdpi.com
The correct concentration of oxygen in all tissues is a hallmark of cellular wellness, and the
negative regulation of oxygen homeostasis is able to affect the cells and tissues of the whole …

Ganoderma lucidum polysaccharide modulates gut microbiota and immune cell function to inhibit inflammation and tumorigenesis in colon

C Guo, D Guo, L Fang, T Sang, J Wu, C Guo… - Carbohydrate …, 2021 - Elsevier
This study investigated the effects of water-soluble polysaccharide extracted from the
sporoderm-removed spores of Ganoderma lucidum (GLP) against AOM/DSS-induced …

The Role of non-coding RNAs in colorectal cancer, with a focus on its autophagy

L Chen, M He, M Zhang, Q Sun, S Zeng, H Zhao… - Pharmacology & …, 2021 - Elsevier
Colorectal cancer (CRC) is one of malignant afflictions burdening people worldwide, mainly
caused by shortages of effective medical intervention and poorly mechanistic understanding …

Nanoparticle-based drug delivery systems in cancer: A focus on inflammatory pathways

AR Afshari, M Sanati, H Mollazadeh… - Seminars in cancer …, 2022 - Elsevier
It has become necessary to accept the clinical reality of therapeutic agents targeting the
cancer-associated immune system. In recent decades, several investigations have …

Oncopreventive and oncotherapeutic potential of licorice triterpenoid compound glycyrrhizin and its derivatives: Molecular insights

R Jain, MA Hussein, S Pierce, C Martens… - Pharmacological …, 2022 - Elsevier
Licorice (Glycyrrhiza glabra) is a well-known natural herb used to treat different ailments
since ancient times. Glycyrrhizin (GL), which is the primary triterpenoid compound of licorice …

Molecular network of colorectal cancer and current therapeutic options

Z Huang, M Yang - Frontiers in oncology, 2022 - frontiersin.org
Colorectal cancer (CRC), a leading cause of cancer-related mortalities globally, results from
the accumulation of multiple genetic and epigenetic alterations in the normal colonic and …

Herb and spices in colorectal cancer prevention and treatment: A narrative review

MS Hossain, MA Kader, KW Goh, M Islam… - Frontiers in …, 2022 - frontiersin.org
Colorectal cancer (CRC) is the second most deadly cancer worldwide. CRC management is
challenging due to late detection, high recurrence rate, and multi-drug resistance. Herbs and …

A comprehensive view on the quercetin impact on colorectal cancer

AA Neamtu, TA Maghiar, A Alaya, NK Olah, V Turcus… - Molecules, 2022 - mdpi.com
Colorectal cancer (CRC) represents the third type of cancer in incidence and second in
mortality worldwide, with the newly diagnosed case number on the rise. Among the …

Gastroprotective effects of polyphenols against various gastro-intestinal disorders: a mini-review with special focus on clinical evidence

HF Chiu, K Venkatakrishnan, O Golovinskaia… - Molecules, 2021 - mdpi.com
Polyphenols are classified as an organic chemical with phenolic units that display an array
of biological functions. However, polyphenols have very low bioavailability and stability …