PSMA radioligand therapy for solid tumors other than prostate cancer: background, opportunities, challenges, and first clinical reports

MJM Uijen, YHW Derks, RIJ Merkx… - European journal of …, 2021 - Springer
In the past decade, a growing body of literature has reported promising results for prostate-
specific membrane antigen (PSMA)-targeted radionuclide imaging and therapy in prostate …

PSMA theranostics: current status and future directions

K Rahbar, A Afshar-Oromieh, H Jadvar… - Molecular …, 2018 - journals.sagepub.com
Prostate-specific membrane antigen (PSMA) is a promising target for imaging diagnostics
and targeted radionuclide therapy (theranostics) of prostate cancer and its metastases …

Imaging of nonprostate cancers using PSMA-targeted radiotracers: rationale, current state of the field, and a call to arms

RAS Fragomeni, T Amir, S Sheikhbahaei… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA) is a type II transmembrane glycoprotein that is
highly overexpressed on prostate cancer epithelial cells and for which there is a growing …

Targeting prostate cancer: prostate‐specific membrane antigen based diagnosis and therapy

T Wüstemann, U Haberkorn, J Babich… - Medicinal research …, 2019 - Wiley Online Library
The high incidence rates of prostate cancer (PCa) raise demand for improved therapeutic
strategies. Prostate tumors specifically express the prostate‐specific membrane antigen …

Targeting PSMA by radioligands in non-prostate disease—current status and future perspectives

P Backhaus, B Noto, N Avramovic, LS Grubert… - European journal of …, 2018 - Springer
Background Prostate-specific membrane antigen (PSMA) is the up-and-coming target for
molecular imaging of prostate cancer. Despite its name, non-prostate-related PSMA …

Hetero-bivalent agents targeting FAP and PSMA

S Boinapally, A Lisok, G Lofland, I Minn, Y Yan… - European Journal of …, 2022 - Springer
Purpose We developed a theranostic radiopharmaceutical that engages two key cell surface
proteases, fibroblast activation protein alpha (FAP) and prostate-specific membrane antigen …

PSMA expression in solid tumors beyond the prostate gland: ready for theranostic applications?

C Lauri, L Chiurchioni, VM Russo, L Zannini… - Journal of Clinical …, 2022 - mdpi.com
In the past decades, the expanding use of prostate-specific membrane antigen (PSMA)
imaging for prostate cancer has led to the incidental detection of a lot of extra-prostatic …

Role of PSMA-ligands imaging in renal cell carcinoma management: current status and future perspectives

L Urso, A Castello, GC Rocca, F Lancia… - Journal of Cancer …, 2022 - Springer
Background Renal masses detection is continually increasing worldwide, with Renal Cell
Carcinoma (RCC) accounting for approximately 90% of all renal cancers and remaining one …

Comprehensive evaluation of 68Ga-PSMA-11 PET/CT parameters for discriminating pathological characteristics in primary clear-cell renal cell carcinoma

J Gao, Q Xu, Y Fu, K He, C Zhang, Q Zhang… - European Journal of …, 2021 - Springer
Purpose To evaluate parameters derived from 68 Ga-PSMA-11 PET/CT images for
discriminating pathological characteristics in primary clear-cell renal cell carcinoma …

[HTML][HTML] Impact of prostate-specific membrane antigen positron emission tomography/computed tomography in the management of oligometastatic renal cell …

C Udovicich, J Callahan, M Bressel, WL Ong… - European Urology Open …, 2022 - Elsevier
Background Prostate-specific membrane antigen (PSMA) is overexpressed in the
neovasculature of renal cell carcinoma (RCC). However, there remains limited evidence …