Drug development, Brazilian biodiversity and political choices: Where are we heading?

PMP Ferreira, DDR Arcanjo… - Journal of Toxicology and …, 2023 - Taylor & Francis
The aim of this review was to (i) acknowledge structural advantages of natural products
(NPs) for designing therapeutic drugs;(ii) emphasize how wildlife conservation is socially …

[HTML][HTML] Phytochemistry and Diverse Pharmacology of Genus Mimosa: A Review

K Rizwan, I Majeed, M Bilal, T Rasheed, A Shakeel… - Biomolecules, 2022 - mdpi.com
The genus Mimosa belongs to the Fabaceae family and comprises almost 400 species of
herbs, shrubs and ornamental trees. The genus Mimosa is found all over the tropics and …

Toxicological, chemopreventive, and cytotoxic potentialities of rare vegetal species and supporting findings for the Brazilian Unified Health System (SUS)

JN Silva, NBN Monção, RRS de Farias… - Journal of Toxicology …, 2020 - Taylor & Francis
Caatinga flora which are found in a poor Brazilian region contain a substantial number of
endemic taxa with biomedical and social importance for regional communities. This study …

Bioassay-Guided Isolation of Fungistatic Compounds from Mimosa caesalpiniifolia Leaves

MJ Dias Silva, AM Simonet, NC Silva… - Journal of natural …, 2019 - ACS Publications
A bioassay-guided phytochemical study of a Mimosa caesalpiniifolia leaf extract with
antifungal activity permitted the identification of 28 compounds, including the new 6-(β …

Phytopharmacological aspects of Mimosa tenuiflora (Willd.) poir.: a systematic review of preclinical data

EO Silva, ML de Souza, NAC de Souza… - Phytochemistry …, 2024 - Springer
Abstract Mimosa tenuiflora (Willd.) Poir. is a native species of tropical regions with a diverse
therapeutic potential due to the presence of various metabolites in its botanical composition …

Chemical composition and diuretic, natriuretic and kaliuretic effects of extracts of Mimosa bimucronata (DC.) Kuntze leaves and its majority constituent methyl gallate …

F Schlickmann, P de Souza, T Boeing… - Journal of Pharmacy …, 2017 - academic.oup.com
Objectives Some species of the genus Mimosa showed promising results in previous
investigations, which include diuretic effect; however, no chemical analyses or animal model …

[HTML][HTML] Cardiovascular effects of farnesol and its β-cyclodextrin complex in normotensive and hypertensive rats

EAP Silva, JS Carvalho, DM Dos Santos… - European Journal of …, 2021 - Elsevier
Farnesol (FAR) is a sesquiterpene alcohol with a range of reported biological effects
including cardioprotective, antioxidant and antiarrhythmic properties. However, due to its …

Gas Chromatography‐Triple Quadrupole Mass Spectrometry Analysis and Vasorelaxant Effect of Essential Oil from Protium heptaphyllum (Aubl.) March.

M Mobin, SG de Lima, LTG Almeida… - BioMed research …, 2017 - Wiley Online Library
The Protium heptaphyllum species, also known as Almécega, produces an oily resin, used
in folk medicine as an analgesic and anti‐inflammatory agent, in healing, and as an …

[HTML][HTML] Chemical profile and evaluation of the pharmacological activity of the dry extract and fraction of ethyl acetate obtained from the leaves of Mimosa …

VC Oliveira, SO Rodrigues, SMT Souto… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Mimosa caesalpiniifolia (Sansão-do-Campo) is a
native species of the caatinga in northeastern Brazil that has been studied for its potential …

Chemotherapeutic and Safety Profile of a Fraction from Mimosa caesalpiniifolia Stem Bark

PM Pinheiro Ferreira, RR Drumond, JN Silva… - Journal of …, 2021 - Wiley Online Library
Mimosa caesalpiniifolia (Fabaceae) is used by Brazilian people to treat hypertension,
bronchitis, and skin infections. Herein, we evaluated the antiproliferative action of the …