Cannabis sativa is the source of a unique set of compounds known collectively as plant
cannabinoids or phytocannabinoids. This review focuses on the manner with which three of …

The cannabis withdrawal syndrome (CWS) is a criterion of cannabis use disorders
(CUDs)(Diagnostic and Statistical Manual of Mental Disorders–Fifth Edition) and cannabis …

The Cannabis sativa herb contains over 100 phytocannabinoid (pCB) compounds and has
been used for thousands of years for both recreational and medicinal purposes. In the past …

There is now a large body of data indicating that the cannabinoid receptor type 2 (CB2) is
linked to a variety of immune events. This functional relevance appears to be most salient in …

It is widely accepted that non-endogenous compounds that target CB1 and/or CB2 receptors
possess therapeutic potential for the clinical management of an ever growing number of …

ABSTRACT A major finding—that (–)‐trans‐Δ9‐tetrahydrocannabinol (Δ9‐THC) is largely
responsible for the psychotropic effects of cannabis—prompted research in the 1970s and …

All four stereoisomers of Δ9‐tetrahydrocannabinol (Δ9‐THC) were synthesized in concise
fashion using stereodivergent dual catalysis. Thus, following identical synthetic sequences …

Cannabinoids enhance the function of glycine receptors (GlyRs). However, little is known
about the mechanisms and behavioral implication of cannabinoid-GlyR interaction. Using …

The endocannabinoid-inactivating enzyme, fatty acid amide hydrolase (FAAH), and the
transient receptor potential vanilloid type-1 (TRPV1) channel are new targets for the …

Menthol belongs to monoterpene class of a structurally diverse group of phytochemicals
found in plant-derived essential oils. Menthol is widely used in pharmaceuticals …