Microbiome-based therapeutics
MT Sorbara, EG Pamer - Nature Reviews Microbiology, 2022 - nature.com
Symbiotic microorganisms inhabiting the gastrointestinal tract promote health by decreasing
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
susceptibility to infection and enhancing resistance to a range of diseases. In this Review …
Microbiota-mediated colonization resistance: mechanisms and regulation
G Caballero-Flores, JM Pickard, G Núñez - Nature Reviews …, 2023 - nature.com
A dense and diverse microbial community inhabits the gut and many epithelial surfaces.
Referred to as the microbiota, it co-evolved with the host and is beneficial for many host …
Referred to as the microbiota, it co-evolved with the host and is beneficial for many host …
[HTML][HTML] The role of microbiota in infant health: from early life to adulthood
Y Yao, X Cai, Y Ye, F Wang, F Chen… - Frontiers in …, 2021 - frontiersin.org
From early life to adulthood, the microbiota play a crucial role in the health of the infant. The
microbiota in early life are not only a key regulator of infant health but also associated with …
microbiota in early life are not only a key regulator of infant health but also associated with …
Key bacterial taxa and metabolic pathways affecting gut short-chain fatty acid profiles in early life
N Tsukuda, K Yahagi, T Hara, Y Watanabe… - The ISME …, 2021 - academic.oup.com
Infant gut microbiota development affects the host physiology throughout life, and short-
chain fatty acids (SCFAs) are promising key metabolites mediating microbiota-host …
chain fatty acids (SCFAs) are promising key metabolites mediating microbiota-host …
MAIT cells are imprinted by the microbiota in early life and promote tissue repair
MG Constantinides, VM Link, S Tamoutounour… - Science, 2019 - science.org
INTRODUCTION The microbiota promotes the maturation and homeostasis of the immune
system, in part through the release of microbial products. Early-life microbial colonization …
system, in part through the release of microbial products. Early-life microbial colonization …
Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease
JM Pickard, MY Zeng, R Caruso… - Immunological …, 2017 - Wiley Online Library
The intestinal tract of mammals is colonized by a large number of microorganisms including
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …
Interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier
EC Martens, M Neumann, MS Desai - Nature Reviews Microbiology, 2018 - nature.com
The intestinal mucosal barrier is composed of epithelial cells that are protected by an
overlying host-secreted mucous layer and functions as the first line of defence against …
overlying host-secreted mucous layer and functions as the first line of defence against …
Healthy infants harbor intestinal bacteria that protect against food allergy
There has been a striking generational increase in life-threatening food allergies in
Westernized societies,. One hypothesis to explain this rising prevalence is that twenty-first …
Westernized societies,. One hypothesis to explain this rising prevalence is that twenty-first …
Defining the role of Parasutterella, a previously uncharacterized member of the core gut microbiota
The genus of Parasutterella has been defined as a core component of the human and
mouse gut microbiota, and has been correlated with various health outcomes. However, like …
mouse gut microbiota, and has been correlated with various health outcomes. However, like …
[HTML][HTML] The commensal microbiota and viral infection: a comprehensive review
N Li, WT Ma, M Pang, QL Fan, JL Hua - Frontiers in Immunology, 2019 - frontiersin.org
The human body is inhabited by a diverse microbial community that is collectively coined as
commensal microbiota. Recent research has greatly advanced our understanding of how …
commensal microbiota. Recent research has greatly advanced our understanding of how …