Ubiquitin ligases: guardians of mammalian development
DA Cruz Walma, Z Chen, AN Bullock… - … Reviews Molecular Cell …, 2022 - nature.com
Mammalian development demands precision. Millions of molecules must be properly
located in temporal order, and their function regulated, to orchestrate important steps in cell …
located in temporal order, and their function regulated, to orchestrate important steps in cell …
[HTML][HTML] Multi-organ proteomic landscape of COVID-19 autopsies
X Nie, L Qian, R Sun, B Huang, X Dong, Q Xiao… - Cell, 2021 - cell.com
The molecular pathology of multi-organ injuries in COVID-19 patients remains unclear,
preventing effective therapeutics development. Here, we report a proteomic analysis of 144 …
preventing effective therapeutics development. Here, we report a proteomic analysis of 144 …
Genetics of hypogonadotropic Hypogonadism—Human and mouse genes, inheritance, oligogenicity, and genetic counseling
ED Louden, A Poch, HG Kim, A Ben-Mahmoud… - Molecular and cellular …, 2021 - Elsevier
Hypogonadotropic hypogonadism, which may be normosmic (nHH) or anosmic/hyposmic,
known as Kallmann syndrome (KS), is due to gonadotropin-releasing hormone deficiency …
known as Kallmann syndrome (KS), is due to gonadotropin-releasing hormone deficiency …
Human semen quality as affected by SARS‐CoV‐2 infection: An up‐to‐date review
SA Banihani - Andrologia, 2022 - Wiley Online Library
Revealing the effect of SARS‐CoV‐2 infection on semen quality is a dynamic priority for
many healthcare providers in the field as well as subfertile patients. Therefore, the collective …
many healthcare providers in the field as well as subfertile patients. Therefore, the collective …
The differential roles for neurodevelopmental and neuroendocrine genes in shaping GnRH neuron physiology and deficiency
R Oleari, V Massa, A Cariboni, A Lettieri - International Journal of …, 2021 - mdpi.com
Gonadotropin releasing hormone (GnRH) neurons are hypothalamic neuroendocrine cells
that control sexual reproduction. During embryonic development, GnRH neurons migrate …
that control sexual reproduction. During embryonic development, GnRH neurons migrate …
[HTML][HTML] Genome-wide association studies uncover genes associated with litter traits in the pig
YX Zhao, GX Gao, Y Zhou, CX Guo, B Li, S El-Ashram… - animal, 2022 - Elsevier
Litter traits are critical economic variables in the pig industry as they represent a production
indicator that can serve to determine sow fertility. In this study, a genome-wide association …
indicator that can serve to determine sow fertility. In this study, a genome-wide association …
Proteolysis in reproduction: lessons from gene-modified organism studies
D Kiyozumi, M Ikawa - Frontiers in Endocrinology, 2022 - frontiersin.org
The physiological roles of proteolysis are not limited to degrading unnecessary proteins.
Proteolysis plays pivotal roles in various biological processes through cleaving peptide …
Proteolysis plays pivotal roles in various biological processes through cleaving peptide …
RNF216 mediates neuronal injury following experimental subarachnoid hemorrhage through the Arc/Arg3. 1‐AMPAR pathway
T Chen, J Zhu, YH Wang - The FASEB Journal, 2020 - Wiley Online Library
Subarachnoid hemorrhage (SAH), mostly caused by aneurysm rupture, is a pathological
condition associated with oxidative stress and neuroinflammation. Toll‐like receptors (TLRs) …
condition associated with oxidative stress and neuroinflammation. Toll‐like receptors (TLRs) …
Clinical and genetic spectrum of RNF216-related disorder: a new case and literature review
C Wu, Z Zhang - Journal of Medical Genetics, 2024 - jmg.bmj.com
Background Cases of RNF216-related disorder have been reported sporadically. However,
the clinical and genetic spectrum of this disorder has not been fully studied. Methods We …
the clinical and genetic spectrum of this disorder has not been fully studied. Methods We …
Application of CRISPR/Cas technology in spermatogenesis research and male infertility treatment
HQ Wang, T Wang, F Gao, WZ Ren - Genes, 2022 - mdpi.com
As the basis of animal reproductive activity, normal spermatogenesis directly determines the
efficiency of livestock production. An in-depth understanding of spermatogenesis will greatly …
efficiency of livestock production. An in-depth understanding of spermatogenesis will greatly …