Parental environmental factors, including diet, body composition, metabolism, and stress,
affect the health and chronic disease risk of people throughout their lives, as captured in the …

Infertility is a global health problem involving about 15% of couples. Approximately half of
the infertility cases are related to male factors. The oxidative stress, which refers to an …

Spermatozoa are highly vulnerable to oxidative attack because they lack significant
antioxidant protection due to the limited volume and restricted distribution of cytoplasmic …

The association between poor paternal diet, perturbed embryonic development, and adult
offspring ill health represents a new focus for the Developmental Origins of Health and …

Besides ATP production, mitochondria are key organelles in several cellular functions, such
as steroid hormone biosynthesis, calcium homoeostasis, intrinsic apoptotic pathway, and the …

This systematic review investigated the effect of paternal obesity on reproductive potential.
Databases searched were Pubmed, Ovid, Web of Science, Scopus, Cinahl and Embase …

Obesity is highly prevalent, and its incidence is increasing. The previous study showing a
major effect of paternal obesity on metabolic health of offspring is confounded by …

The increasing occurrence of obesity has become a significant public health concern.
Individuals with obesity have higher prevalence of heart disease, stroke, osteoarthritis …

Oxidative stress occurs when the production of potentially destructive reactive oxygen
species (ROS) exceeds the bodies own natural antioxidant defenses, resulting in cellular …

Male obesity in reproductive-age men has nearly tripled in the past 30 y and coincides with
an increase in male infertility worldwide. There is now emerging evidence that male obesity …