Recent years have seen tremendous progress towards therapy of many previously incurable
neuromuscular diseases. This new context has acted as a driving force for the development …

Due to its exceptional sensitivity to soft tissues, MRI has been extensively utilized to assess
anatomical muscle parameters such as muscle volume and cross‐sectional area …

The purpose of this study was to evaluate temporal stability, multi‐center reproducibility and
the influence of covariates on a multimodal MR protocol for quantitative muscle imaging and …

OBJECTIVE. For many years, MRI of the musculoskeletal system has relied mostly on
conventional sequences with qualitative analysis. More recently, using quantitative MRI …

Objectives Magnetic resonance imaging (MRI) constitutes a powerful outcome measure in
neuromuscular disorders, yet there is a broad diversity of approaches in data acquisition …

A growing body of the literature supports the use of magnetic resonance imaging as a
potential biomarker for disease severity in the hereditary myopathies. We performed a …

Purpose Multi‐echo spin‐echo (MSE) transverse relaxometry mapping using multi‐
component models is used to study disease activity in neuromuscular disease by assessing …

Background Duchenne muscular dystrophy (DMD) is a hereditary neuromuscular disease
leading to progressive muscle wasting. Since there is a need for MRI variables that serve as …

Objective A number of promising experimental therapies for Duchenne muscular dystrophy
(DMD) are emerging. Clinical trials currently rely on invasive biopsies or motivation …

In the last years, magnetic resonance imaging (MRI) has become fundamental for the
diagnosis and monitoring of myopathies given its ability to show the severity and distribution …