Biomolecular interactions underpin most processes inside the cell. Hence, a precise and
quantitative understanding of molecular association and dissociation events is crucial, not …

Understanding the dynamic interactions of ligands to DNA is important in DNA-based
nanotechnologies. By structurally tracking the dissociation of Hoechst 33258-bound DNA (d …

Cell death is an important life activity in individual development. Changes in morphological
and mechanical properties during cell death are crucial to identify the modes of cell death …

Specific identification of enterohemorrhagic Escherichia coli was achieved using
microspheres coated with overoxidized polypyrrole. The microspheres are well dispersed in …

The dynamic topological structure of telomeric DNA is closely related to its biological
function; however, no such structural information on full-length telomeric DNA has been …

It is important for elucidating the regulation mechanism of life activities, as well as for the
prevention, diagnosis, and drug design of diseases, to study protein–protein interactions …

Most of the anticancer drugs bind to double-stranded DNA (dsDNA) by intercalative-binding
mode. Although experimental studies have become available recently, a molecular-level …

In this work we study the structure-transport property relationships of small ligand
intercalated DNA molecules using a multiscale modeling approach where extensive ab initio …

The binding constant of receptors for small molecules, proteins, or antibodies is usually
determined based on the concentrations of the ligand, receptor, and their complexes. The …

Cations‐induced DNA aggregation can modify the local structure of oligonucleotides and
has potential applications in medicine and biotechnology. Here, we used atomic force …