[HTML][HTML] Swine as biomedical animal model for T-cell research—Success and potential for transmittable and non-transmittable human diseases

T Käser - Molecular immunology, 2021 - Elsevier
Swine is biologically one of the most relevant large animal models for biomedical research.
With its use as food animal that can be exploited as a free cell and tissue source for research …

Impacts of F18+ Escherichia coli on Intestinal Health of Nursery Pigs and Dietary Interventions

ME Duarte, Y Garavito-Duarte, SW Kim - Animals, 2023 - mdpi.com
Simple Summary The modern intensive practices in pig production to enhance productivity
have increased post-weaning diarrhea (PWD), often caused by F18+ Escherichia coli …

Enteromorpha prolifera polysaccharide–zinc complex modulates the immune response and alleviates LPS-induced intestinal inflammation via inhibiting the TLR4/NF …

Y Zhang, X Duan, T Wassie, H Wang, T Li, C Xie… - Food & function, 2022 - pubs.rsc.org
Enteromorpha prolifera polysaccharide–zinc (EP–Zn), a kind of polysaccharide–zinc
complex, has been shown to improve the immune response and reduce the inflammatory …

A Proteomic Approach to elucidate the changes in saliva and serum proteins of Pigs with septic and non-septic inflammation

MJ López-Martínez, JJ Cerón, A Ortín-Bustillo… - International journal of …, 2022 - mdpi.com
Sepsis is a systemic inflammatory response triggered by an infectious agent and is
recognized by the World Health Organization as a global concern, since it is one of the …

Regional epithelial cell diversity in the small intestine of pigs

JE Wiarda, SR Becker, SK Sivasankaran… - Journal of Animal …, 2023 - academic.oup.com
Understanding regional distribution and specialization of small intestinal epithelial cells is
crucial for developing methods to control appetite, stress, and nutrient uptake in swine. To …

Evaluation of the use of prenatal immune stimulation to alter postnatal immune function in weaned pigs

NC Burdick Sanchez, T Mitchell… - Frontiers in Animal …, 2024 - frontiersin.org
This study was designed to determine whether exposure to low-dose endotoxin
(lipopolysaccharide; LPS) during gestation can enhance immunity to a subsequent LPS …

Qihuzha granule attenuated LPS-induced acute spleen injury in mice via Src/MAPK/Stat3 signal pathway

T Zhong, M Feng, M Su, D Wang, Q Li, S Jia… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Qihuzha granule (QHZG), is one of traditional Chinese
patent medicines composed of eleven edible medicinal plant, which has been used in the …

Transcriptomic analysis of intestinal organoids, derived from pigs divergent in feed efficiency, and their response to Escherichia coli

O Madsen, RSC Rikkers, JM Wells, R Bergsma, SK Kar… - BMC genomics, 2024 - Springer
Background There is increasing interest in using intestinal organoids to study complex traits
like feed efficiency (FE) and host-microbe interactions. The aim of this study was to …

Analysis of merged whole blood transcriptomic datasets to identify circulating molecular biomarkers of feed efficiency in growing pigs

F Messad, I Louveau, D Renaudeau, H Gilbert… - BMC genomics, 2021 - Springer
Background Improving feed efficiency (FE) is an important goal due to its economic and
environmental significance for farm animal production. The FE phenotype is complex and …

Vaginal microbiota diversity in response to lipopolysaccharide in gilts housed under three housing systems

L Alves, FJ de Novais, AN da Silva, MS Araujo… - Frontiers in …, 2022 - frontiersin.org
The United Kingdom and European Union have banned crates for pregnant sows. However,
animals are kept in a restrictive environment for up to four weeks after mating, leading to …