Ocular PK is the science behind the kinetics of drug distribution throughout, and its
elimination from, ocular tissue. Ocular pharmacodynamics (PD) is the science quantifying …

Purpose: Previous studies have shown that iris mechanical properties may play a role in the
pathophysiology of primary angle-closure glaucoma (PACG). Such studies, however, were …

Background Disclosing the mechanism of primary angle closure glaucoma with pupillary
block is important to the diagnosis as well as treatments, such as the laser peripheral …

Aim Previous studies have shown that the trabecular meshwork (TM) is mechanically stiffer
in glaucomatous eyes as compared to normal eyes. It is believed that elevated TM stiffness …

Pupil blocking force (PBF) can indicate the potential risk of pupil block (PB), which is
considered as a main pathogenic factor of primary angle‐closure glaucoma (PACG) …

Purpose.: To investigate the contribution of three anatomical and physiologic factors (dilator
thickness, dynamic pupillary block, and iris compressibility) to changes in iris configuration …

Objectives: Describe the etiology of pigment dispersion syndrome. Review the
pathophysiology of pigment dispersion syndrome. Summarize the findings in pigment …

The iris plays an important role in certain types of glaucoma, including primary angle-closure
glaucoma and pigmentary glaucoma. Iris mechanics are also important in influencing …

Background/aims To identify ocular determinants of iridolenticular contact area (ILCA), a
recently introduced swept-source optical coherence tomography (SSOCT) derived …

Quantifying the mechanical properties of the iris is important, as it provides insight into the
pathophysiology of glaucoma. Recent ex vivo studies have shown that the mechanical …