Aryl nitriles are widely found in natural products, pharmaceuticals, agrochemicals, dyes, and
herbicides. Moreover, because the cyano group can be easily converted into various …

Nitriles unveil widespread applications in pharmaceuticals, agrochemicals, textiles, rubber,
polymers, and constitute a significant intermediate in several organic transformations …

The development of sustainable protocols for synthesis of aromatic nitriles from
corresponding alcohols using metal-free heterogenous catalysts is a challenging task. In this …

Robotic platforms for chemistry are developing rapidly but most systems are not currently
able to adapt to changing circumstances in real-time. We present a dynamically …

The synthetic use of molecular iodine is described. Iodine is a universal oxidizing agent,
especially for the oxidation of alcohols and aldehydes to esters, nitriles and amides. Further …

The parasites that give rise to human African trypanosomiasis (HAT) are auxotrophs for
various nutrients from the human host, including purines. They have specialist nucleoside …

An enantioselective synthesis of INCB018424 via organocatalytic asymmetric aza-Michael
addition of pyrazoles (16 or 20) to (E)-3-cyclopentylacrylaldehyde (23) using diarylprolinol …

Facile oxidative conversion of alcohols to esters using molecular iodine - ScienceDirect Skip
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A variety of aldehydes reacted with iodine in ammonia water at room temperature to give the
nitrile intermediates, which were trapped by addition of hydrogen peroxide, sodium azide, or …

A series of primary alcohols and aldehydes were treated with iodine in ammonia water
under microwave irradiation to give the intermediate nitriles, which without isolation …