Information decomposition and the informational architecture of the brain

AI Luppi, FE Rosas, PAM Mediano, DK Menon… - Trends in Cognitive …, 2024 - cell.com
To explain how the brain orchestrates information-processing for cognition, we must
understand information itself. Importantly, information is not a monolithic entity. Information …

Greater than the parts: a review of the information decomposition approach to causal emergence

PAM Mediano, FE Rosas, AI Luppi… - … of the Royal …, 2022 - royalsocietypublishing.org
Emergence is a profound subject that straddles many scientific disciplines, including the
formation of galaxies and how consciousness arises from the collective activity of neurons …

PLD3 affects axonal spheroids and network defects in Alzheimer's disease

P Yuan, M Zhang, L Tong, TM Morse, RA McDougal… - Nature, 2022 - nature.com
The precise mechanisms that lead to cognitive decline in Alzheimer's disease are unknown.
Here we identify amyloid-plaque-associated axonal spheroids as prominent contributors to …

Robotic hand augmentation drives changes in neural body representation

P Kieliba, D Clode, RO Maimon-Mor, TR Makin - Science robotics, 2021 - science.org
Humans have long been fascinated by the opportunities afforded through augmentation.
This vision not only depends on technological innovations but also critically relies on our …

Multimodal perception links cellular state to decision-making in single cells

BA Kramer, J Sarabia del Castillo, L Pelkmans - Science, 2022 - science.org
Individual cells make decisions that are adapted to their internal state and surroundings, but
how cells can reliably do this remains unclear. To study the information processing capacity …

Brain-wide interactions during hippocampal sharp wave ripples

N Nitzan, R Swanson, D Schmitz… - Proceedings of the …, 2022 - National Acad Sciences
During periods of disengagement from the environment, transient population bursts, known
as sharp wave ripples (SPW-Rs), occur sporadically. While numerous experiments have …

Transfer entropy as a measure of brain connectivity: A critical analysis with the help of neural mass models

M Ursino, G Ricci, E Magosso - Frontiers in computational …, 2020 - frontiersin.org
Objective: Assessing brain connectivity from electrophysiological signals is of great
relevance in neuroscience, but results are still debated and depend crucially on how …

Hierarchical representations of aggression in a hypothalamic-midbrain circuit

AL Falkner, D Wei, A Song, LW Watsek, I Chen, P Chen… - Neuron, 2020 - cell.com
Although the ventromedial hypothalamus ventrolateral area (VMHvl) is now well established
as a critical locus for the generation of conspecific aggression, its role is complex, with …

Bidirectional control of fear memories by cerebellar neurons projecting to the ventrolateral periaqueductal grey

JL Frontera, H Baba Aissa, RW Sala… - Nature …, 2020 - nature.com
Fear conditioning is a form of associative learning that is known to involve different brain
areas, notably the amygdala, the prefrontal cortex and the periaqueductal grey (PAG). Here …

Non-linear dimensionality reduction on extracellular waveforms reveals cell type diversity in premotor cortex

EK Lee, H Balasubramanian, A Tsolias, SU Anakwe… - Elife, 2021 - elifesciences.org
Cortical circuits are thought to contain a large number of cell types that coordinate to
produce behavior. Current in vivo methods rely on clustering of specified features of …