Soon after its discovery, microRNA-9 (miR-9) attracted the attention of neurobiologists, since
it is one of the most highly expressed microRNAs in the developing and adult vertebrate …

African annual fishes from the genus Nothobranchius are small teleosts that inhabit
temporary water bodies subject to annual desiccation due to the alternation of the monsoon …

The killifish Nothobranchius furzeri is the shortest-lived vertebrate that can be bred in the
laboratory. Its rapid growth, early sexual maturation, fast aging, and arrested embryonic …

A progressive loss of protein homeostasis is characteristic of aging and a driver of
neurodegeneration. To investigate this process quantitatively, we characterized proteome …

The African turquoise killifish has recently gained significant traction as a new research
organism in the aging field. Our understanding of aging has strongly benefited from …

Neuronal migration is a critical process in the development of the nervous system. Defects in
the migration of the neurons are associated with diseases like lissencephaly, subcortical …

The brains of teleost fish show extensive adult neurogenesis and neuronal regeneration.
The patterns of gene regulation during fish brain aging are unknown. The short‐lived teleost …

Turquoise killifish, Nothobranchius furzeri, have an intrinsically short life span, with a median
life span of< 6 months and a maximum (90%) life span of 9 months. This short life span …

Human ageing is a fundamental biological process that leads to functional decay, increased
risk for various diseases and, ultimately, death. Some of the basic biological mechanisms …

At birth or after hatching from the egg, vertebrate brains still contain neural stem cells which
reside in specialized niches. In some cases, these stem cells are deployed for further …