High glutathione production is known to be one of the defense mechanisms by which many
cancer cells survive elevated oxidative stress. By explicitly targeting glutathione in these …

Aims To present the recent update on the isolation, engineering techniques for extracellular
vesicles, limitations associated with different isolation techniques, different biomedical …

Polymeric micelles (PMs) have demonstrated significant impact as potential cargo carriers,
primarily due to their exceptional physicochemical features. One of the major concerns in the …

Pharmacokinetic (PK) elucidation of polymeric micelles delivering anticancer drugs is crucial
for accurate antitumor PK-pharmacodynamic (PK–PD) simulations. Particularly, establishing …

Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease where standard-of-care
chemotherapeutic drugs have limited efficacy due to the development of drug resistance and …

To synthesize an effective and versatile nano-platform serving as a promising carrier for
controlled drug delivery, visible-light-induced diselenide-crosslinked polyurethane micelles …

Amphiphilic functional polycaprolactone (PCL) diblock copolymers are excellent candidates
for micellar drug delivery. The functional groups on the backbone significantly affect the …

Local anesthesia is essential in dental practices, particularly for managing pain in tooth
socket wounds, yet improving drug delivery systems remains a significant challenge. This …

Amphiphilic helical polycarbodiimides bearing side chains with terminal alkyne groups
provide a unique platform for construction of polymeric micelles. Incorporation of propargyl …

Despite the advent of novel therapeutics, efficient delivery of antineoplastic drugs remains a
challenge. Biodegradable polymeric micelles represent a promising frontier by offering …