Intranasal drug delivery: opportunities and toxicologic challenges during drug development
LA Keller, O Merkel, A Popp - Drug delivery and translational research, 2022 - Springer
Over the past 10 years, the interest in intranasal drug delivery in pharmaceutical R&D has
increased. This review article summarises information on intranasal administration for local …
increased. This review article summarises information on intranasal administration for local …
Clinical practice guideline: nosebleed (epistaxis)
Objective Nosebleed, also known as epistaxis, is a common problem that occurs at some
point in at least 60% of people in the United States. While the majority of nosebleeds are …
point in at least 60% of people in the United States. While the majority of nosebleeds are …
Nasoseptal perforation: from etiology to treatment
C Pereira, A Santamaría, C Langdon… - Current allergy and …, 2018 - Springer
Abstract Purpose of Review Nasal septum perforation (NSP) is a communication between
the two nasal cavities. This review contributes to the better knowledge of NSP causes …
the two nasal cavities. This review contributes to the better knowledge of NSP causes …
Advances and challenges in intranasal delivery of antipsychotic agents targeting the central nervous system
Treatment of central nervous system (CNS) disorders is challenging using conventional
delivery strategies and routes of administration because of the presence of the blood–brain …
delivery strategies and routes of administration because of the presence of the blood–brain …
Bioactive components of different nasal spray solutions may defeat SARS-Cov2: Repurposing and in silico studies
Abstract The recent outbreak “Coronavirus Disease 2019 (COVID-19)” is caused by fast-
spreading and highly contagious severe acute respiratory syndrome coronavirus 2 (SARS …
spreading and highly contagious severe acute respiratory syndrome coronavirus 2 (SARS …
Challenges in the development and application of organ-on-chips for intranasal drug delivery studies
With the growing demand for the development of intranasal (IN) products, such as nasal
vaccines, which has been especially highlighted during the COVID-19 pandemic, the lack of …
vaccines, which has been especially highlighted during the COVID-19 pandemic, the lack of …
[HTML][HTML] Sympathomimetic amine compounds and hepatotoxicity: not all are alike—key distinctions noted in a short review
C Willson - Toxicology reports, 2019 - Elsevier
Sympathomimetic amine compounds are often pooled together and incorrectly assumed to
be interchangeable with respect to potential adverse effects. A brief and specific review of …
be interchangeable with respect to potential adverse effects. A brief and specific review of …
Rise and fall of decongestants in treating nasal congestion related diseases
J Wang, ZF Mao, L Cheng - Expert Opinion on Pharmacotherapy, 2024 - Taylor & Francis
Introduction Decongestants are commonly used drugs in clinical practice, and they can
relieve nasal congestion caused by factors like influenza, rhinitis, and acute upper …
relieve nasal congestion caused by factors like influenza, rhinitis, and acute upper …
Topical nasal decongestant oxymetazoline: Safety considerations for perioperative pediatric use
R Cartabuke, JD Tobias, KR Jatana - Pediatrics, 2021 - publications.aap.org
Background Oxymetazoline hydrochloride 0.05% is the active ingredient in over-the-counter
(OTC) nasal spray decongestants (eg, Afrin; Merck Schering-Plough Pharmaceuticals, North …
(OTC) nasal spray decongestants (eg, Afrin; Merck Schering-Plough Pharmaceuticals, North …
[PDF][PDF] Effect of micronized cellulose powder on the efficacy of topical oxymetazoline in allergic rhinitis
Background: Defective nasal barrier function is implicated in allergic rhinitis, which results in
persistent inflammation and clinical symptoms, among which congestion plays a prominent …
persistent inflammation and clinical symptoms, among which congestion plays a prominent …