Myeloperoxidase (MPO) is a member of the superfamily of heme peroxidases that is mainly
expressed in neutrophils and monocytes. MPO-derived reactive species play a key role in …

The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …

Flavonoids are a class of secondary plant phenolics with significant antioxidant and
chelating properties. In the human diet, they are most concentrated in fruits, vegetables …

At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

The primary β-globin gene mutation that causes sickle cell disease (SCD) has significant
pathophysiological consequences that result in hemolytic events and the induction of the …

Neutrophilic polymorphonuclear leukocytes (neutrophils) are highly specialized for their
primary function, the phagocytosis and destruction of microorganisms. When coated with …

This review focuses on the role of oxidative processes in atherosclerosis and its resultant
cardiovascular events. There is now a consensus that atherosclerosis represents a state of …

Vitamin C readily scavenges reactive oxygen and nitrogen species and may thereby prevent
oxidative damage to important biological macromolecules such as DNA, lipids, and proteins …

Providing a comprehensive review of reactions of oxidation for different classes of organic
compounds and polymers, and biological processes mediated by free radicals, Oxidation …

Myeloperoxidase (MPO) belongs to the heme peroxidase family, which includes a set of
enzymes with potent oxidoreductase activity. MPO is considered an important part of the …