Sex-specific differences in hypertension and associated cardiovascular disease

KMM Colafella, KM Denton - Nature Reviews Nephrology, 2018 - nature.com
Although intrinsic mechanisms that regulate arterial blood pressure (BP) are similar in men
and women, marked variations exist at the molecular, cellular and tissue levels. These …

Sex and gender differences in myocarditis and dilated cardiomyopathy: an update

DL Fairweather, DJ Beetler, N Musigk… - Frontiers in …, 2023 - frontiersin.org
In the past decade there has been a growing interest in understanding sex and gender
differences in myocarditis and dilated cardiomyopathy (DCM), and the purpose of this review …

Sex differences in endothelial function important to vascular health and overall cardiovascular disease risk across the lifespan

AE Stanhewicz, MM Wenner… - American Journal of …, 2018 - journals.physiology.org
Diseases of the cardiovascular system are the leading cause of morbidity and mortality in
men and women in developed countries, and cardiovascular disease (CVD) is becoming …

Hypertension: renin–angiotensin–aldosterone system alterations

L Te Riet, JHM van Esch, AJM Roks… - Circulation …, 2015 - Am Heart Assoc
Blockers of the renin–angiotensin–aldosterone system (RAAS), that is, renin inhibitors,
angiotensin (Ang)-converting enzyme (ACE) inhibitors, Ang II type 1 receptor antagonists …

Sex differences in blood pressure regulation and hypertension: renal, hemodynamic, and hormonal mechanisms

ER Drury, J Wu, JC Gigliotti, TH Le - Physiological Reviews, 2024 - journals.physiology.org
The teleology of sex differences has been argued since at least as early as Aristotle's
controversial Generation of Animals more than 300 years BC, which reflects the sex bias of …

Sex and gender differences in chronic kidney disease: progression to end-stage renal disease and haemodialysis

G Cobo, M Hecking, FK Port, I Exner… - Clinical …, 2016 - portlandpress.com
Sex and gender differences are of fundamental importance in most diseases, including
chronic kidney disease (CKD). Men and women with CKD differ with regard to the …

Sex-specific physiology and cardiovascular disease

CL Shufelt, C Pacheco, MS Tweet, VM Miller - Sex-Specific Analysis of …, 2018 - Springer
Sex differences in cardiovascular diseases can be classified as those which are specific to
one sex and those that differ in incidence, prevalence, etiology, symptomatology, response …

Heart failure subtypes and cardiomyopathies in women

EM DeFilippis, A Beale, T Martyn, A Agarwal… - Circulation …, 2022 - Am Heart Assoc
Heart failure affects over 2.6 million women and 3.4 million men in the United States with
known sex differences in epidemiology, management, response to treatment, and outcomes …

Gender and the renin–angiotensin–aldosterone system

K Komukai, S Mochizuki… - Fundamental & clinical …, 2010 - Wiley Online Library
Premenopausal women are protected to some extent from cardiovascular and kidney
diseases. Because this protection weakens after menopause, sex hormones are believed to …

The “his and hers” of the renin-angiotensin system

LM Hilliard, AK Sampson, RD Brown… - Current hypertension …, 2013 - Springer
Sex differences exist in the regulation of arterial pressure and renal function by the renin-
angiotensin system (RAS). This may in part stem from a differential balance in the pressor …