Embryo-scale, single-cell spatial transcriptomics

SR Srivatsan, MC Regier, E Barkan, JM Franks… - Science, 2021 - science.org
Spatial patterns of gene expression manifest at scales ranging from local (eg, cell-cell
interactions) to global (eg, body axis patterning). However, current spatial transcriptomics …

Histology atlas of the developing mouse heart with emphasis on E11. 5 to E18. 5

SM Savolainen, JF Foley… - Toxicologic pathology, 2009 - journals.sagepub.com
In humans, congenital heart diseases are common. Since the rapid progression of
transgenic technologies, the mouse has become the major animal model of defective …

Morphometrics, 3D imaging, and craniofacial development

B Hallgrimsson, CJ Percival, R Green… - Current topics in …, 2015 - Elsevier
Recent studies have shown how volumetric imaging and morphometrics can add
significantly to our understanding of morphogenesis, the developmental basis for variation …

Rapid 3D phenotyping of cardiovascular development in mouse embryos by micro-CT with iodine staining

K Degenhardt, AC Wright, D Horng… - Circulation …, 2010 - Am Heart Assoc
Background—Microcomputed tomography (micro-CT) has been used extensively in
research to generate high-resolution 3D images of calcified tissues in small animals …

An MRI-based atlas and database of the developing mouse brain

N Chuang, S Mori, A Yamamoto, H Jiang, X Ye, X Xu… - Neuroimage, 2011 - Elsevier
The advent of mammalian gene engineering and genetically modified mouse models has
led to renewed interest in developing resources for referencing and quantitative analysis of …

Micro MRI of the mouse brain using a novel 400 MHz cryogenic quadrature RF probe

C Baltes, N Radzwill, S Bosshard… - NMR in Biomedicine …, 2009 - Wiley Online Library
The increasing number of mouse models of human disease used in biomedical research
applications has led to an enhanced interest in non‐invasive imaging of mice, eg using MRI …

Post-mortem examination of human fetuses: a comparison of whole-body high-field MRI at 9· 4 T with conventional MRI and invasive autopsy

S Thayyil, JO Cleary, NJ Sebire, RJ Scott, K Chong… - The Lancet, 2009 - thelancet.com
Background Conventional whole-body MRI at 1· 5 T does not provide adequate image
quality of small fetuses, thus reducing its potential for use as an alternative to invasive …

Magnetic resonance microscopy defines ethanol‐induced brain abnormalities in prenatal mice: effects of acute insult on gestational day 8

SE Parnell, SK O'Leary‐Moore… - Alcoholism: Clinical …, 2009 - Wiley Online Library
Background: Magnetic resonance microscopy (MRM), magnetic resonance imaging (MRI) at
microscopic levels, provides unprecedented opportunities to aid in defining the full spectrum …

Neurite orientation dispersion and density imaging of mouse brain microstructure

N Wang, J Zhang, G Cofer, Y Qi, RJ Anderson… - Brain Structure and …, 2019 - Springer
Advanced biophysical models like neurite orientation dispersion and density imaging
(NODDI) have been developed to estimate the microstructural complexity of voxels enriched …

Design of a novel class of protein‐based magnetic resonance imaging contrast agents for the molecular imaging of cancer biomarkers

S Xue, J Qiao, F Pu, M Cameron… - Wiley Interdisciplinary …, 2013 - Wiley Online Library
Magnetic resonance imaging (MRI) of disease biomarkers, especially cancer biomarkers,
could potentially improve our understanding of the disease and drug activity during …