WHO estimated that nearly 1 million people become infected every day with any of four
curable sexually transmitted infections (STIs): chlamydia, gonorrhoea, syphilis, and …

Sexually transmitted infections (STIs) caused by Neisseria gonorrhoeae, Chlamydia
trachomatis and Mycoplasma genitalium are a common cause of pelvic inflammatory …

Peptide-chain elongation during protein synthesis entails sequential aminoacyl-tRNA
selection and translocation reactions that proceed rapidly (2–20 per second) and with a low …

Farnesoid X receptor (FXR) is a promising target for nonalcoholic steatohepatitis (NASH)
and fibrosis. Although various FXR agonists have shown anti-fibrotic effects in diverse …

Gonorrhea and antimicrobial resistance (AMR) in Neisseria gonorrhoeae are major public
health concerns globally. Dual antimicrobial therapy (mainly ceftriaxone 250–500 mg× 1 …

Mycobacterium abscessus (Mab), a nontuberculous mycobacterial (NTM) species, is an
emerging pathogen with high intrinsic drug resistance. Current standard-of-care therapy …

Vancomycin has long been considered a drug of last resort. Its efficiency in treating multiple
drug‐resistant bacterial infections, particularly methicillin‐resistant Staphylococcus aureus …

Ribosomes, which synthesize proteins, are critical organelles for the survival and growth of
bacteria. About 60% of approved antibiotics discovered so far combat pathogenic bacteria …

Spectinamides are a novel class of antitubercular agents with the potential to treat drug-
resistant tuberculosis infections. Their antitubercular activity is derived from both ribosomal …

Bacterial sexually transmitted infections are widespread and common, with Neisseria
gonorrhoeae (gonorrhea) and Chlamydia trachomatis (chlamydia) being the two most …