Molecular subtypes and local-regional control of breast cancer

SM Fragomeni, A Sciallis… - Surgical Oncology …, 2018 - surgonc.theclinics.com
Breast cancer is a heterogeneous disease that affects one anatomic site, yet is
phenotypically variable. 1, 2 The identification of different biological subtypes occurs …

[HTML][HTML] Triple negative breast cancer: a mountain yet to be scaled despite the triumphs

Q Wu, S Siddharth, D Sharma - Cancers, 2021 - mdpi.com
Simple Summary Triple-negative breast cancer (TNBC) is a highly aggressive subtype of
breast cancer that cannot be treated with endocrine therapy and Her2-targeted therapy …

[HTML][HTML] Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early …

A Goldhirsch, EP Winer, AS Coates, RD Gelber… - Annals of oncology, 2013 - Elsevier
Abstract The 13th St Gallen International Breast Cancer Conference (2013) Expert Panel
reviewed and endorsed substantial new evidence on aspects of the local and regional …

[HTML][HTML] The association of surgical margins and local recurrence in women with early-stage invasive breast cancer treated with breast-conserving therapy: a meta …

N Houssami, P Macaskill, M Luke Marinovich… - Annals of surgical …, 2014 - Springer
Purpose There is no consensus on what constitutes adequate negative margins in breast-
conserving therapy (BCT). We systematically review the evidence on surgical margins in …

Margins in breast cancer: How much is enough?

M Pilewskie, M Morrow - Cancer, 2018 - Wiley Online Library
The appropriate negative margin width for women undergoing breast‐conserving surgery for
both ductal carcinoma in situ (DCIS) and invasive carcinoma is controversial. This review …

Breast surgery for metastatic breast cancer

G Tosello, MR Torloni, BS Mota… - Cochrane Database …, 2018 - cochranelibrary.com
Background Metastatic breast cancer is not a curable disease, but women with metastatic
disease are living longer. Surgery to remove the primary tumour is associated with an …

Locoregional control according to breast cancer subtype and response to neoadjuvant chemotherapy in breast cancer patients undergoing breast-conserving therapy

SK Swisher, J Vila, SL Tucker, I Bedrosian… - Annals of surgical …, 2016 - Springer
Background Our group previously published data showing that patients could be stratified by
constructed molecular subtype with respect to locoregional recurrence (LRR)-free survival …

Contralateral prophylactic mastectomy after unilateral breast cancer: a systematic review and meta-analysis

OM Fayanju, CRT Stoll, S Fowler, GA Colditz… - Annals of …, 2014 - journals.lww.com
Objective: To examine whether contralateral prophylactic mastectomy (CPM) is associated
with improved survival, incidence of contralateral breast cancer (CBC), and recurrence in …

[HTML][HTML] Local recurrence following breast-conserving treatment in women aged 40 years or younger: trends in risk and the impact on prognosis in a population-based …

C Van Laar, MJC Van Der Sangen… - European Journal of …, 2013 - Elsevier
Aim To evaluate trends in the risk of local recurrences after breast-conserving treatment
(BCT) and to examine the impact of local recurrence (LR) on distant relapse-free survival in …

Cardiac outcomes of patients receiving adjuvant weekly paclitaxel and trastuzumab for node-negative, ERBB2-positive breast cancer

C Dang, H Guo, J Najita, D Yardley, K Marcom… - JAMA …, 2016 - jamanetwork.com
Importance Trastuzumab is a life-saving therapy but is associated with symptomatic and
asymptomatic left ventricular ejection fraction (LVEF) decline. We report the cardiac toxic …