[HTML][HTML] Genetic manipulation and tools in myxobacteria for the exploitation of secondary metabolism
X Yue, D Sheng, L Zhuo, YZ Li - Engineering Microbiology, 2023 - Elsevier
Myxobacteria are famous for their capacity for social behavior and natural product
biosynthesis. The unique sociality of myxobacteria is not only an intriguing scientific topic but …
biosynthesis. The unique sociality of myxobacteria is not only an intriguing scientific topic but …
[HTML][HTML] Multiple chaperonins in bacteria—novel functions and non-canonical behaviors
Chaperonins are a class of molecular chaperones that assemble into a large double ring
architecture with each ring constituting seven to nine subunits and enclosing a cavity for …
architecture with each ring constituting seven to nine subunits and enclosing a cavity for …
Extraordinary expansion of a Sorangium cellulosum genome from an alkaline milieu
K Han, Z Li, R Peng, L Zhu, T Zhou, L Wang, S Li… - Scientific reports, 2013 - nature.com
Complex environmental conditions can significantly affect bacterial genome size by
unknown mechanisms. The So0157-2 strain of Sorangium cellulosum is an alkaline …
unknown mechanisms. The So0157-2 strain of Sorangium cellulosum is an alkaline …
Construction and comparison of synthetic microbial consortium system (SMCs) by non-living or living materials immobilization and application in acetochlor …
J Liu, X Zhou, T Wang, L Fan, S Liu, N Wu, A Xu… - Journal of Hazardous …, 2022 - Elsevier
The microbial degradation of pesticides by pure or mixed microbial cultures has been
thoroughly explored, however, they are still difficult to apply in real environmental …
thoroughly explored, however, they are still difficult to apply in real environmental …
Deficiency in cytosine DNA methylation leads to high chaperonin expression and tolerance to aminoglycosides in Vibrio cholerae
Antibiotic resistance has become a major global issue. Understanding the molecular
mechanisms underlying microbial adaptation to antibiotics is of keen importance to fight …
mechanisms underlying microbial adaptation to antibiotics is of keen importance to fight …
A novel stress response mechanism, triggered by indole, involved in quorum quenching enzyme MomL and iron-sulfur cluster in Muricauda olearia Th120
Y Wang, H Li, X Cui, XH Zhang - Scientific Reports, 2017 - nature.com
Indole, as a signal molecule, is involved in multiple physiological behavior including biofilm
formation, antibiotic resistance and virulence. In this study, we demonstrated that indole was …
formation, antibiotic resistance and virulence. In this study, we demonstrated that indole was …
Dosage constraint of the ribosome-associated molecular chaperone drives the evolution and fates of its duplicates in bacteria
T Wan, L Zhuo, Z Pan, R Chen, H Ma, Y Cao, J Wang… - Mbio, 2024 - journals.asm.org
Gene duplication events happen prevalently during evolution, and the mechanisms
governing the loss or retention of duplicated genes are mostly elusive. Our genome …
governing the loss or retention of duplicated genes are mostly elusive. Our genome …
A Dual-Functional Orphan Response Regulator Negatively Controls the Differential Transcription of Duplicate groEL s and Plays a Global Regulatory Role in …
Differential transcription of functionally divergent duplicate genes is critical for bacterial cells
to properly and competitively function in the environment, but the transcriptional regulation …
to properly and competitively function in the environment, but the transcriptional regulation …
Allopatric integrations selectively change host transcriptomes, leading to varied expression efficiencies of exotic genes in Myxococcus xanthus
LP Zhu, XJ Yue, K Han, ZF Li, LS Zheng, XN Yi… - Microbial Cell …, 2015 - Springer
Background Exotic genes, especially clustered multiple-genes for a complex pathway, are
normally integrated into chromosome for heterologous expression. The influences of …
normally integrated into chromosome for heterologous expression. The influences of …
Effects of transcriptional mode on promoter substitution and tandem engineering for the production of epothilones in Myxococcus xanthus
Promoter optimization is an economical and effective approach to overexpress heterologous
genes and improve the biosynthesis of valuable products. In this study, we swapped the …
genes and improve the biosynthesis of valuable products. In this study, we swapped the …