Organic carbamates in drug design and medicinal chemistry

AK Ghosh, M Brindisi - Journal of medicinal chemistry, 2015 - ACS Publications
The carbamate group is a key structural motif in many approved drugs and prodrugs. There
is an increasing use of carbamates in medicinal chemistry and many derivatives are …

Antimicrobial peptides: key components of the innate immune system

M Pasupuleti, A Schmidtchen… - Critical reviews in …, 2012 - Taylor & Francis
Life-threatening infectious diseases are on their way to cause a worldwide crisis, as treating
them effectively is becoming increasingly difficult due to the emergence of antibiotic resistant …

Multi‐layer 3D Chirality and Double‐Helical Assembly in a Copper Nanocluster with a Triple‐Helical Cu15 Core

G Dong, Z Pan, B Han, Y Tao, X Chen… - Angewandte Chemie …, 2023 - Wiley Online Library
Conceptually mimicking biomolecules' ability to construct multiple‐helical aggregates with
emergent properties and functions remains a long‐standing challenge. Here we report an …

Recent developments in asymmetric multicomponent reactions

C de Graaff, E Ruijter, RVA Orru - Chemical Society Reviews, 2012 - pubs.rsc.org
Multicomponent reactions (MCRs) receive increasing attention because they address both
diversity and complexity in organic synthesis. Thus, in principle diverse sets of relatively …

Aromatic amide foldamers: structures, properties, and functions

DW Zhang, X Zhao, JL Hou, ZT Li - Chemical reviews, 2012 - ACS Publications
The past several decades have witnessed great progress in the understanding of the high-
order structure of biomacromolecules. Currently, it is well-recognized that folding of proteins …

The catalytic amination of alcohols

S Bähn, S Imm, L Neubert, M Zhang… - …, 2011 - Wiley Online Library
In this Minireview, the synthesis of amines by the amination of alcohols, by means of the so‐
called borrowing hydrogen methodology, is presented. Compared to other synthetic …

Fluorescent labeling of biomolecules with organic probes

MST Gonçalves - Chemical reviews, 2009 - ACS Publications
Many areas of modern technology are dependent on sensitive analytical techniques, and
this is particularly true for environmental science, medicine, pharmacy, and cellular biology …

Coordination− insertion copolymerization of fundamental polar monomers

A Nakamura, S Ito, K Nozaki - Chemical reviews, 2009 - ACS Publications
Akifumi Nakamura (left) was born in 1984 in Kanagawa, Japan. He received his BS degree
in 2007 and MS degree in 2009 from the University of Tokyo under the guidance of …

Self-assembly, bioactivity, and nanomaterials applications of peptide conjugates with bulky aromatic terminal groups

IW Hamley - ACS Applied Bio Materials, 2023 - ACS Publications
The self-assembly and structural and functional properties of peptide conjugates containing
bulky terminal aromatic substituents are reviewed with a particular focus on bioactivity …

Contemporary strategies for peptide macrocyclization

CJ White, AK Yudin - Nature chemistry, 2011 - nature.com
Peptide macrocycles have found applications that range from drug discovery to
nanomaterials. These ring-shaped molecules have shown remarkable capacity for …