The creation of breast lesion models for mammographic virtual clinical trials: a topical review

A Van Camp, K Houbrechts, L Cockmartin… - Progress in …, 2023 - iopscience.iop.org
Simulated breast lesion models, including microcalcification clusters and masses, have
been used in several studies. Realistic lesion models are required for virtual clinical trials to …

Design and validation of realistic breast models for use in multiple alternative forced choice virtual clinical trials

P Elangovan, A Mackenzie, DR Dance… - Physics in Medicine …, 2017 - iopscience.iop.org
A novel method has been developed for generating quasi-realistic voxel phantoms which
simulate the compressed breast in mammography and digital breast tomosynthesis (DBT) …

Development and validation of a modelling framework for simulating 2D-mammography and breast tomosynthesis images

P Elangovan, LM Warren, A Mackenzie… - Physics in Medicine …, 2014 - iopscience.iop.org
Planar 2D x-ray mammography is generally accepted as the preferred screening technique
used for breast cancer detection. Recently, digital breast tomosynthesis (DBT) has been …

The simulation of 3D microcalcification clusters in 2D digital mammography and breast tomosynthesis

E Shaheen, C Van Ongeval, F Zanca… - Medical …, 2011 - Wiley Online Library
Purpose: This work proposes a new method of building 3D models of microcalcification
clusters and describes the validation of their realistic appearance when simulated into 2D …

The simulation of 3D mass models in 2D digital mammography and breast tomosynthesis

E Shaheen, F De Keyzer, H Bosmans… - Medical …, 2014 - Wiley Online Library
Purpose: This work proposes a new method of building 3D breast mass models with
different morphological shapes and describes the validation of the realism of their …

Verification of the accuracy of a hybrid breast imaging simulation framework for virtual clinical trial applications

L Vancoillie, N Marshall, L Cockmartin… - Journal of Medical …, 2020 - spiedigitallibrary.org
Purpose: The impact of system parameters on signal detectability can be studied with
simulation platforms. We describe the steps taken to verify and confirm the accuracy of a …

Quantification of scattered radiation in projection mammography: four practical methods compared

E Salvagnini, H Bosmans, L Struelens… - Medical …, 2012 - Wiley Online Library
Purpose: Four different practical methodologies of quantifying scattered radiation for two
different digital mammographic systems are compared. The study considered both grid in …

Investigation of the effect of tube motion in breast tomosynthesis: continuous or step and shoot?

E Shaheen, N Marshall… - Medical Imaging 2011 …, 2011 - spiedigitallibrary.org
Digital breast tomosynthesis (DBT) is a 3D modality that may have the potential to
complement or replace 2D mammography. One major design aspect of DBT systems is the …

Impact of compressed breast thickness and dose on lesion detectability in digital mammography: FROC study with simulated lesions in real mammograms

E Salvagnini, H Bosmans, C Van Ongeval… - Medical …, 2016 - Wiley Online Library
Purpose: The aim of this work was twofold:(1) to examine whether, with standard automatic
exposure control (AEC) settings that maintain pixel values in the detector constant, lesion …

Lesion detectability in 2D-mammography and digital breast tomosynthesis using different targets and observers

P Elangovan, A Mackenzie, DR Dance… - Physics in Medicine …, 2018 - iopscience.iop.org
This work investigates the detection performance of specialist and non-specialist observers
for different targets in 2D-mammography and digital breast tomosynthesis (DBT) using the …