Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Heavy-atom-free photosensitizers: from molecular design to applications in the photodynamic therapy of cancer

VN Nguyen, Y Yan, J Zhao, J Yoon - Accounts of chemical …, 2020 - ACS Publications
Conspectus Photodynamic therapy (PDT) is a clinically approved therapeutic modality that
has shown great potential for the treatment of cancers owing to its excellent spatiotemporal …

BODIPY‐based photodynamic agents for exclusively generating superoxide radical over singlet oxygen

KX Teng, WK Chen, LY Niu, WH Fang… - Angewandte Chemie …, 2021 - Wiley Online Library
Developing Type‐I photosensitizers is considered as an efficient approach to overcome the
deficiency of traditional photodynamic therapy (PDT) for hypoxic tumors. However, it remains …

Molecular design of highly efficient heavy‐atom‐free triplet BODIPY derivatives for photodynamic therapy and bioimaging

VN Nguyen, Y Yim, S Kim, B Ryu… - Angewandte Chemie …, 2020 - Wiley Online Library
Novel BODIPY photosensitizers were developed for imaging‐guided photodynamic therapy.
The introduction of a strong electron donor to the BODIPY core through a phenyl linker …

Heavy atom‐free, mitochondria‐targeted, and activatable photosensitizers for photodynamic therapy with real‐time in‐situ therapeutic monitoring

J Miao, Y Huo, G Yao, Y Feng, J Weng… - Angewandte Chemie …, 2022 - Wiley Online Library
Based on spin‐orbit charge transfer intersystem crossing mechanism, two heavy‐atom‐free
photosensitizers (PSs) BDP1/BDP2 with absorption maxima at 506 nm/660 nm were …

Recent development of heavy-atom-free triplet photosensitizers: molecular structure design, photophysics and application

X Zhang, Z Wang, Y Hou, Y Yan, J Zhao… - Journal of Materials …, 2021 - pubs.rsc.org
Triplet photosensitizers (PSs) have attracted much attention in recent years, due to the
significance of these kinds of compounds in fundamental photochemistry studies and …

Recent development of the transition metal complexes showing strong absorption of visible light and long-lived triplet excited state: From molecular structure design to …

X Zhang, Y Hou, X Xiao, X Chen, M Hu, X Geng… - Coordination Chemistry …, 2020 - Elsevier
Transition metal complexes have been studied for decades due to their interesting
photophysical processes and their applications in photocatalysis, photodynamic therapy …

Mechanism of ultrafast triplet exciton formation in single cocrystals of π-stacked electron donors and acceptors

ML Williams, I Schlesinger… - Journal of the …, 2022 - ACS Publications
Ultrafast triplet formation in donor–acceptor (D–A) systems typically occurs by spin–orbit
charge-transfer intersystem crossing (SOCT-ISC), which requires a significant orbital …

Supramolecular assembly boosting the phototherapy performances of BODIPYs

Y Dai, J Sun, X Zhang, J Zhao, W Yang, J Zhou… - Coordination Chemistry …, 2024 - Elsevier
Phototherapies, including photodynamic therapy (PDT) and photothermal therapy (PTT),
have emerged as leading research areas in chemistry, materials science, and medicine …

Triplet photosensitizers showing strong absorption of visible light and long-lived triplet excited states and application in photocatalysis: A mini review

X Zhao, Y Hou, L Liu, J Zhao - Energy & Fuels, 2021 - ACS Publications
Triplet photosensitizers (PSs) have been studied as photocatalysts in photocatalytic H2
evolution by water splitting and photoredox catalytic synthetic organic reactions, etc. The …