Pharmacomicrobiomics of Classical Immunosuppressant Drugs: A Systematic Review

A Manes, T Di Renzo, L Dodani, A Reale, C Gautiero… - Biomedicines, 2023 - mdpi.com
The clinical response to classical immunosuppressant drugs (cIMDs) is highly variable
among individuals. We performed a systematic review of published evidence supporting the …

The advances in adjuvant therapy for tuberculosis with immunoregulatory compounds

J Mi, X Wu, J Liang - Frontiers in Microbiology, 2024 - frontiersin.org
Tuberculosis (TB) is a chronic bacterial disease, as well as a complex immune disease. The
occurrence, development, and prognosis of TB are not only related to the pathogenicity of …

Effects of Everolimus in Modulating the Host Immune Responses against Mycobacterium tuberculosis Infection

A Raien, S Davis, M Zhang, D Zitser, M Lin, G Pitcher… - Cells, 2023 - mdpi.com
The phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin
(P13K/AKT/mTOR) pathway plays a key role in tuberculosis (TB) pathogenesis and infection …

Unraveling the potential of graphene quantum dots against Mycobacterium tuberculosis infection

G Santarelli, G Perini, A Salustri, I Palucci… - Frontiers in …, 2024 - frontiersin.org
Introduction The emergence of drug-resistant Mycobacterium tuberculosis (Mtb) strains has
underscored the urgent need for novel therapeutic approaches. Carbon-based …

Host-directed therapy against mycobacterium tuberculosis infections with diabetes mellitus

L Zhao, K Fan, X Sun, W Li, F Qin, L Shi, F Gao… - Frontiers in …, 2024 - frontiersin.org
Tuberculosis (TB) is caused by the bacterial pathogen Mycobacterium tuberculosis (MTB)
and is one of the principal reasons for mortality and morbidity worldwide. Currently …