Since currently available antipsychotic medications predominantly treat hallucinations,
delusions, disorganized thoughts and behavior, and related agitation/aggression, attention …

Negative symptoms (such as amotivation and diminished expression) associated with
schizophrenia are a major health concern. Adequate treatment would mean important …

One of the most widely used guides to prescribing psychiatric medications, the Tenth Edition
of Maudsley Prescribing Guidelines returns with fully updated content and new sections on …

BACKGROUND: Emerging evidence from clinical trials suggests that oral estrogen and
intranasal oxytocin might reduce symptom severity in schizophrenia. Whether increases in …

Testosterone products are recommended by some prescribers in response to a diagnosis or
presumption of “low testosterone”(low-T) for cardiovascular health, sexual function, muscle …

The peak in incidence for schizophrenia is during late adolescence for both sexes, but within
this time frame the peak is both earlier and steeper for males. Additionally, women have a …

In general, rigorous data on combination therapy in schizophrenia are rare and further
randomized controlled trials, naturalistic trials and head-to-head-trials are necessary. Some …

Since the discovery of chlorpromazine in the 1950's, antipsychotic drugs have been the
cornerstone of treatment of schizophrenia, and all attenuate dopamine transmission at the …

Gonadal hormones are becoming increasingly recognized for their effects on cognition.
Estrogens, in particular, have received attention for their effects on learning and memory that …

Sex is a significant source of heterogeneity in schizophrenia, with more negative symptoms
in males and more affective symptoms and internalizing comorbidity in females. In this …