Calcific aortic valve disease (CAVD) is a highly prevalent condition that comprises a disease
continuum, ranging from microscopic changes to profound fibro-calcific leaflet remodelling …

Calcific aortic valve disease sits at the confluence of multiple world-wide epidemics of aging,
obesity, diabetes, and renal dysfunction, and its prevalence is expected to nearly triple over …

The extracellular vesicle (EV) surface proteome (surfaceome) acts as a fundamental
signalling gateway by bridging intra‐and extracellular signalling networks, dictates EVs' …

Matrix vesicles (MVs) have shown strong effects in diseases such as vascular ectopic
calcification and pathological calcified osteoarthritis and in wound repair of the skeletal …

Extracellular vesicles (EVs) have been implicated mechanistically in the pathobiology of
neurodegenerative disorders, including central nervous system injury. However, the role of …

Hydrogels, which are hydrophilic polymer networks, have attracted great attention, and
significant advances in their biological and biomedical applications, such as for drug …

This review provides a comprehensive overview of our understanding of the role that
glycans play in the formation, loading and release of extracellular vesicles (EVs). The …

Extracellular vesicles (EVs) are small membrane-bound vesicles secreted into the
extracellular space by all cell types. EVs transfer their cargo which includes nucleic acids …

Hypercalcemia and hyperphosphatemia associate with an elevated risk of cardiovascular
events, yet the pathophysiological basis of this association is unclear. Disturbed mineral …

The molecular heterogeneity of extracellular vesicles (EVs) and the co‐isolation of
physically similar particles, such as lipoproteins (LPs), confounds and limits the sensitivity of …