Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer associated with
advanced age and immunosuppression. Over the past decade, an association has been …

Protein and lipid transport along the endolysosomal system of eukaryotic cells depends on
multiple fusion and fission events. Over the past few years, the molecular constituents of …

During the past 6 years, focused virus hunting has led to the discovery of nine new human
polyomaviruses, including Merkel cell polyomavirus, which has been linked to Merkel cell …

Merkel cell carcinoma (MCC) is an aggressive neuroendocrine carcinoma of the skin with
two distinct etiologies. Clonal integration of Merkel cell polyomavirus DNA into the tumor …

About a fifth of all human cancers worldwide are caused by infectious agents. In 12% of
cancers, seven different viruses have been causally linked to human oncogenesis: Epstein …

Viruses are the cause of approximately 15% of all human cancers. Both RNA and DNA
human tumor viruses have been identified, with Merkel cell polyomavirus being the most …

A marked escalation in the rate of discovery of new types of human polyomavirus has
occurred over the last five years largely owing to recent technological advances in their …

Many viruses use overprinting (alternate reading frame utilization) as a means to increase
protein diversity in genomes severely constrained by size. However, the evolutionary steps …

The name of the family Polyomaviridae, derives from the early observation that cells infected
with murine polyomavirus induced multiple (poly) tumors (omas) in immunocompromised …

Merkel cell carcinoma (MCC) frequently contains integrated copies of Merkel cell
polyomavirus DNA that express a truncated form of Large T antigen (LT) and an intact Small …