American Society of Hematology 2019 guidelines for management of venous thromboembolism: prevention of venous thromboembolism in surgical hospitalized …
DR Anderson, GP Morgano, C Bennett… - Blood …, 2019 - ashpublications.org
Background: Venous thromboembolism (VTE) is a common source of perioperative
morbidity and mortality. Objective: These evidence-based guidelines from the American …
morbidity and mortality. Objective: These evidence-based guidelines from the American …
[HTML][HTML] Trauma-induced coagulopathy
Uncontrolled haemorrhage is a major preventable cause of death in patients with traumatic
injury. Trauma-induced coagulopathy (TIC) describes abnormal coagulation processes that …
injury. Trauma-induced coagulopathy (TIC) describes abnormal coagulation processes that …
[HTML][HTML] The European guideline on management of major bleeding and coagulopathy following trauma
DR Spahn, B Bouillon, V Cerny, J Duranteau… - Critical care, 2019 - Springer
Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …
around the world, and post-traumatic bleeding remains a leading cause of potentially …
[HTML][HTML] The European guideline on management of major bleeding and coagulopathy following trauma
R Rossaint, B Bouillon, V Cerny, TJ Coats, J Duranteau… - Critical care, 2016 - Springer
Background Severe trauma continues to represent a global public health issue and mortality
and morbidity in trauma patients remains substantial. A number of initiatives have aimed to …
and morbidity in trauma patients remains substantial. A number of initiatives have aimed to …
An introduction to systematic reviews
Chapter 1 discussed the ways that reviews examine previous research and other forms of
evidence to answer review questions and how their methods depend upon the questions …
evidence to answer review questions and how their methods depend upon the questions …
The systemic immune response to trauma: an overview of pathophysiology and treatment
Improvements in the control of haemorrhage after trauma have resulted in the survival of
many people who would otherwise have died from the initial loss of blood. However, the …
many people who would otherwise have died from the initial loss of blood. However, the …
Recruitment and retention of participants in randomised controlled trials: a review of trials funded and published by the United Kingdom Health Technology …
SJ Walters, IB dos Anjos Henriques-Cadby… - BMJ open, 2017 - bmjopen.bmj.com
Background Substantial amounts of public funds are invested in health research worldwide.
Publicly funded randomised controlled trials (RCTs) often recruit participants at a slower …
Publicly funded randomised controlled trials (RCTs) often recruit participants at a slower …
The many roles of tranexamic acid: an overview of the clinical indications for TXA in medical and surgical patients
J Cai, J Ribkoff, S Olson… - European journal of …, 2020 - Wiley Online Library
Clinically significant bleeding can occur as a consequence of surgery, trauma, obstetric
complications, anticoagulation, and a wide variety of disorders of hemostasis. As the causes …
complications, anticoagulation, and a wide variety of disorders of hemostasis. As the causes …
[HTML][HTML] Acute fibrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study
FCF Schmitt, V Manolov, J Morgenstern… - Annals of intensive …, 2019 - Springer
Background Septic coagulopathy represents a very dynamic disease entity, tilting from initial
hypercoagulability towards a subsequent hypocoagulable disease state, entitled overt …
hypercoagulability towards a subsequent hypocoagulable disease state, entitled overt …
Tranexamic acid–an old drug still going strong and making a revival
L Tengborn, M Blombäck, E Berntorp - Thrombosis research, 2015 - Elsevier
Experience with tranexamic acid, an indirect fibrinolytic inhibitor, started as soon as it was
released from Shosuke Okamoto's lab in the early 1960s. It was first prescribed to females …
released from Shosuke Okamoto's lab in the early 1960s. It was first prescribed to females …