The dose makes the poison: nutritional overload determines the life traits of blood-feeding arthropods
M Sterkel, JHM Oliveira, V Bottino-Rojas… - Trends in …, 2017 - cell.com
Vertebrate blood composition is heavily biased towards proteins, and hemoglobin, which is
a hemeprotein, is by far the most abundant protein. Typically, hematophagous insects ingest …
a hemeprotein, is by far the most abundant protein. Typically, hematophagous insects ingest …
The role of bacterial symbionts in triatomines: an evolutionary perspective
N Salcedo-Porras, C Umaña-Diaz… - Microorganisms, 2020 - mdpi.com
Insects have established mutualistic symbiotic interactions with microorganisms that are
beneficial to both host and symbiont. Many insects have exploited these symbioses to …
beneficial to both host and symbiont. Many insects have exploited these symbioses to …
Catalase protects Aedes aegypti from oxidative stress and increases midgut infection prevalence of Dengue but not Zika
JHM Oliveira, OAC Talyuli… - PLoS neglected …, 2017 - journals.plos.org
Background Digestion of blood in the midgut of Aedes aegypti results in the release of pro-
oxidant molecules that can be toxic to the mosquito. We hypothesized that after a blood …
oxidant molecules that can be toxic to the mosquito. We hypothesized that after a blood …
Field-collected Triatoma sordida from central Brazil display high microbiota diversity that varies with regard to developmental stage and intestinal segmentation
JL Oliveira, JC Cury, R Gurgel-Gonçalves… - PLoS Neglected …, 2018 - journals.plos.org
Background/Methodology Triatomine bugs are the vectors of Trypanosoma cruzi, the agent
of Chagas disease. Vector control has for decades relied upon insecticide spraying, but …
of Chagas disease. Vector control has for decades relied upon insecticide spraying, but …
Rhodnius prolixus: From classical physiology to modern developmental biology
R Nunes‐da‐Fonseca, M Berni, V Tobias‐Santos… - genesis, 2017 - Wiley Online Library
The hemiptera Rhodnius prolixus is a blood‐feeding insect and a primary vector of
Trypanosoma cruzi, the etiological agent of the Chagas disease. Over the past century …
Trypanosoma cruzi, the etiological agent of the Chagas disease. Over the past century …
Expression of Proteins, Glycoproteins, and Transcripts in the Guts of Fasting, Fed, and Trypanosoma cruzi-Infected Triatomines: A Systematic Review
OA Reynoso-Ducoing, B Gonzalez-Rete, E Diaz… - Pathogens, 2023 - mdpi.com
Chagas disease is caused by the hemoflagellate protozoan Trypanosoma cruzi. The main
transmission mechanism for the parasite in endemic areas is contact with the feces of an …
transmission mechanism for the parasite in endemic areas is contact with the feces of an …
Rapamycin inhibits pathogen transmission in mosquitoes by promoting immune activation
Y Feng, L Chen, L Gao, L Dong, H Wen, X Song… - PLoS …, 2021 - journals.plos.org
Repeated blood meals provide essential nutrients for mosquito egg development and routes
for pathogen transmission. The target of rapamycin, the TOR pathway, is essential for …
for pathogen transmission. The target of rapamycin, the TOR pathway, is essential for …
Digestive α-L-fucosidase activity in Rhodnius prolixus after blood feeding: effect of secretagogue and nutritional stimuli
MVF Gama, YN Alexandre, JM Pereira da Silva… - Frontiers in …, 2023 - frontiersin.org
Introduction: Rhodnius prolixus (Hemiptera: Reduviidae) is an important vector of
Trypanosoma cruzi, the causative agent of Chagas Disease. This insect is a model for the …
Trypanosoma cruzi, the causative agent of Chagas Disease. This insect is a model for the …
Silencing of Iron and Heme-Related Genes Revealed a Paramount Role of Iron in the Physiology of the Hematophagous Vector Rhodnius prolixus
AB Walter-Nuno, ML Taracena, RD Mesquita… - Frontiers in …, 2018 - frontiersin.org
Iron is an essential element for most organisms However, free iron and heme, its complex
with protoporphyrin IX, can be extremely cytotoxic, due to the production of reactive oxygen …
with protoporphyrin IX, can be extremely cytotoxic, due to the production of reactive oxygen …
Non-immune traits triggered by blood intake impact vectorial competence
Blood-feeding arthropods are considered an enormous public health threat. They are
vectors of a plethora of infectious agents that cause potentially fatal diseases like Malaria …
vectors of a plethora of infectious agents that cause potentially fatal diseases like Malaria …