[HTML][HTML] Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome
R Lv, X Liu, Y Zhang, N Dong, X Wang, Y He… - Signal transduction and …, 2023 - nature.com
Obstructive sleep apnea syndrome (OSAS) is a common breathing disorder in sleep in
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …
which the airways narrow or collapse during sleep, causing obstructive sleep apnea. The …
The current knowledge concerning solid cancer and therapy
Solid cancers comprise a large number of new cases and deaths from cancer each year
globally. There are a number of strategies for addressing tumors raised from solid organs …
globally. There are a number of strategies for addressing tumors raised from solid organs …
[HTML][HTML] Reshaping the tumour immune microenvironment in solid tumours via tumour cell and immune cell DNA methylation: from mechanisms to therapeutics
F Zhong, Y Lin, L Zhao, C Yang, Y Ye… - British Journal of Cancer, 2023 - nature.com
In recent years, the tumour microenvironment (TME) of solid tumours has attracted more and
more attention from researchers, especially those non-tumour components such as immune …
more attention from researchers, especially those non-tumour components such as immune …
[HTML][HTML] CENPA promotes clear cell renal cell carcinoma progression and metastasis via Wnt/β-catenin signaling pathway
Q Wang, J Xu, Z Xiong, T Xu, J Liu, Y Liu… - Journal of translational …, 2021 - Springer
Clear cell renal cell carcinoma (ccRCC) is the most common malignant tumor of the kidney.
New and reliable biomarkers are in urgent need for ccRCC diagnosis and prognosis. The …
New and reliable biomarkers are in urgent need for ccRCC diagnosis and prognosis. The …
[HTML][HTML] SUV39H1 deficiency suppresses clear cell renal cell carcinoma growth by inducing ferroptosis
J Wang, X Yin, W He, W Xue, J Zhang… - Acta Pharmaceutica Sinica …, 2021 - Elsevier
Clear cell renal cell carcinoma (ccRCC) is a common kidney malignancy characterized by a
poor prognosis. Suppressor of variegation 3–9 homolog 1 (SUV39H1), which encodes a …
poor prognosis. Suppressor of variegation 3–9 homolog 1 (SUV39H1), which encodes a …
Epigenetic activation of RBM15 promotes clear cell renal cell carcinoma growth, metastasis and macrophage infiltration by regulating the m6A modification of CXCL11
X Zeng, K Chen, L Li, J Tian, W Ruan, Z Hu… - Free Radical Biology …, 2022 - Elsevier
Clear cell renal cell carcinoma (ccRCC) is a common kidney malignancy that is
characterized by poor prognosis. RNA-binding motif protein 15 (RBM15) has been identified …
characterized by poor prognosis. RNA-binding motif protein 15 (RBM15) has been identified …
Epigenetic modifications from arsenic exposure: A comprehensive review
A Chakraborty, S Ghosh, B Biswas, S Pramanik… - Science of the total …, 2022 - Elsevier
Arsenic is a notorious element with the potential to harm exposed individuals in ways that
include cancerous and non-cancerous health complications. Millions of people across the …
include cancerous and non-cancerous health complications. Millions of people across the …
[HTML][HTML] PRMT1 is a novel molecular therapeutic target for clear cell renal cell carcinoma
J Wang, C Wang, P Xu, X Li, Y Lu, D Jin, X Yin… - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Background and Objective: Epigenetic alterations are common events in clear cell
renal cell carcinoma (ccRCC), and protein arginine methyltransferase 1 (PRMT1) is an …
renal cell carcinoma (ccRCC), and protein arginine methyltransferase 1 (PRMT1) is an …
[HTML][HTML] Molecular mechanisms in clear cell renal cell carcinoma: role of miRNAs and hypermethylated miRNA genes in crucial oncogenic pathways and processes
EA Braga, MV Fridman, VI Loginov, AA Dmitriev… - Frontiers in …, 2019 - frontiersin.org
Clear cell renal cell carcinoma (ccRCC) is the third most common urological cancer, and it
has the highest mortality rate. The increasing drug resistance of metastatic ccRCC has …
has the highest mortality rate. The increasing drug resistance of metastatic ccRCC has …
[HTML][HTML] TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy
T Song, S Lv, X Ma, X Zhao, L Fan, Q Zou, N Li… - Journal of Biological …, 2023 - ASBMB
Autophagy plays a pivotal role in physiology and pathophysiology, including cancer.
Mechanisms of autophagy dysregulation in cancer remain elusive. Loss of function of …
Mechanisms of autophagy dysregulation in cancer remain elusive. Loss of function of …