New opportunities and old challenges in the clinical translation of nanotheranostics

PJ Gawne, M Ferreira, M Papaluca, J Grimm… - Nature reviews …, 2023 - nature.com
Nanoparticle-based systems imbued with both diagnostic and therapeutic functions, known
as nanotheranostics, have enabled remarkable progress in guiding focal therapy, inducing …

Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Radiolabelling of nanomaterials for medical imaging and therapy

J Pellico, PJ Gawne, RTM de Rosales - Chemical Society Reviews, 2021 - pubs.rsc.org
Nanomaterials offer unique physical, chemical and biological properties of interest for
medical imaging and therapy. Over the last two decades, there has been an increasing effort …

Development of nanotechnology-mediated precision radiotherapy for anti-metastasis and radioprotection

Y Pan, W Tang, W Fan, J Zhang, X Chen - Chemical Society Reviews, 2022 - pubs.rsc.org
Radiotherapy (RT), including external beam RT and internal radiation therapy, uses high-
energy ionizing radiation to kill tumor cells. However, ionizing radiation inevitably damages …

Targeted extracellular vesicle delivery systems employing superparamagnetic iron oxide nanoparticles

Z Zhuo, J Wang, Y Luo, R Zeng, C Zhang, W Zhou… - Acta biomaterialia, 2021 - Elsevier
In the past decade, the study of extracellular vesicles (EVs), especially exosomes (50–150
nm) have attracted growing interest in numerous areas of cancer and tissue regeneration …

Applications of titanium dioxide nanostructure in stomatology

S Liu, X Chen, M Yu, J Li, J Liu, Z Xie, F Gao, Y Liu - Molecules, 2022 - mdpi.com
Breakthroughs in the field of nanotechnology, especially in nanochemistry and
nanofabrication technologies, have been attracting much attention, and various …

Ligand engineering of titanium-oxo nanoclusters for Cerenkov radiation-reinforced photo/chemodynamic tumor therapy

J Li, S Dai, R Qin, C Shi, J Ming, X Zeng… - … applied materials & …, 2021 - ACS Publications
The therapeutic effect of general photodynamic therapy (PDT) is gravely limited by the poor
penetration depth of exogenous light radiation. In recent years, Cerenkov radiation (CR) has …

Aggregation-induced emission photosensitizer/bacteria biohybrids enhance Cerenkov radiation-induced photodynamic therapy by activating anti-tumor immunity for …

Z Zhu, Q Liu, K Zhu, K Wang, L Lin, Y Chen, F Shao… - Acta Biomaterialia, 2023 - Elsevier
Cerenkov radiation-induced photodynamic therapy (CR-PDT) gets rid of the limited tissue
penetration depth of the external light source and provides a feasible scheme for the PDT …

Cubic DNA nanocage-based three-dimensional molecular beacon for accurate detection of exosomal miRNAs in confined spaces

D Mao, M Zheng, W Li, Y Xu, C Wang, Q Qian… - Biosensors and …, 2022 - Elsevier
In situ nondestructive bioanalysis of targets in nanoscale confined space, eg exosomes,
poses a high challenge to analytical technologies, especially to molecular fluorescent …

Pathogenesis and treatment of multiple myeloma

P Yang, Y Qu, M Wang, B Chu, W Chen, Y Zheng… - MedComm, 2022 - Wiley Online Library
Multiple myeloma (MM) is the second‐ranking malignancy in hematological tumors. The
pathogenesis of MM is complex with high heterogeneity, and the development of the …