Aging has a major detrimental effect on the optimal function of the ovary with changes in this
organ preceding the age-related deterioration in other tissues, with the middle-aged …

Amphiregulin (AREG) is an epidermal growth factor (EGF)-like growth factor that binds
exclusively to the EGF receptor (EGFR). Treatment with luteinizing hormone (LH) and/or …

Steroidogenic acute regulatory protein (StAR) mediates the rate-limiting step in ovarian
steroidogenesis and progesterone (P4) synthesis. Melatonin and its receptors are …

Context Fos null mice failed to ovulate and form a corpus luteum (CL) even when given
exogenous gonadotropins, suggesting that ovarian Fos expression is critical for successful …

Background Heparin-binding epidermal growth factor-like growth factor (HB-EGF) belongs
to the epidermal growth factor (EGF) family of growth factors. HB-EGF and its receptors …

Background Cumulus cells (CC) encapsulate growing oocytes and support their growth and
development. Transcriptomic signatures of CC have the potential to serve as valuable non …

Abstract Activating transcription factor 6 (ATF6), a sensor protein located in the endoplasmic
reticulum (ER) membrane, is an important factor in the ER stress signaling pathway. ER …

Context: In animal models, the luteinizing hormone surge increases progesterone (P4) and
progesterone receptor (PGR), prostaglandins (PTGs), and epidermal growth factor (EGF) …

Steroidogenic acute regulatory protein (StAR) plays a critical role in the regulation of
progesterone (P4) production. Resveratrol (RSV), a natural polyphenol, has beneficial …

Mitochondria play a crucial role in the occurrence and development of tumors. We used
mitochondria-related genes for consistent clustering to identify three stable molecular …