The principles of green chemistry (GC) can be comprehensively implemented in green
synthesis of pharmaceuticals by choosing no solvents or green solvents (preferably water) …

The synthesis of amides is of huge importance in a wide variety of industrial and academic
fields and is of particular significance in the synthesis of pharmaceuticals. Many of the well …

Large-Scale Applications of Amide Coupling Reagents for the Synthesis of Pharmaceuticals |
Organic Process Research & Development ACS ACS Publications C&EN CAS Find my …

The direct mechanochemical amidation of esters by ball milling is described. The
operationally simple procedure requires an ester, an amine, and substoichiometric KOtBu …

Chemical reactions for the formation of amide bonds are among the most commonly used
transformations in organic chemistry, yet they are often highly inefficient. A novel protocol for …

Solvents represent one of the major contributions to the environmental impact of fine‐
chemical synthesis. As a result, the use of environmentally friendly solvents in widely …

In the last few decades, photocatalytic radical carbonylation strategies have received
considerable attention as they are becoming a formidable tool in the toolbox of organic …

Lanthanum trifluoromethanesulfonate is an effective single-component catalyst for
synthesizing a variety of amides directly from esters and amines under mild conditions …

The highly efficient transamidation of several primary, secondary, and tertiary amides with
aliphatic and aromatic amines (primary and secondary) is described. The reaction is …

In the micelle of PS-750-M, the presence of 3° amides from the surfactant proline linker
mimics dimethylformamide, dimethylacetamide, and N-methyl-2-pyrrolidone. The resultant …