PARPs and tankyrases (TNKS) represent a family of 17 proteins. PARPs and tankyrases
were originally identified as DNA repair factors, nevertheless, recent advances have shed …

Myosin is a molecular motor, which interacts with actin to convert the energy from ATP
hydrolysis into mechanical work. In cardiac myocytes, two myosin isoforms are expressed …

The purpose of this review is to present current understanding of cellular and molecular
regulation of fibre type expression in skeletal muscle. Published literature seems to …

Abstract Poly (ADP-ribose) polymerases (PARPs or ARTDs), originally described as DNA
repair factors, have metabolic regulatory roles. PARP1, PARP2, PARP7, PARP10, and …

Abstract Poly (ADP-ribose) polymerase 1 (PARP-1) is an abundant nuclear enzyme involved
in DNA repair. The therapeutic efficacy of drugs that inhibit PARP-1 in various disorders …

Chromatin regulation provides an important means for controlling cardiac gene expression
under different physiological and pathological conditions. Processes that direct the …

Skeletal Muscle Plasticity: Cellular and Molecular Responses... : American Journal of Physical
Medicine & Rehabilitation Skeletal Muscle Plasticity: Cellular and Molecular Responses to …

Abstract We examined YAP1/TAZ-TEAD signaling pathway activity at neuromuscular
junctions (NMJs) of skeletal muscle fibers in adult mice. Our investigations revealed that …

Poly (ADP-ribose) polymerase-1 (PARP), a chromatin-bound enzyme, is activated by cell
oxidative stress. Because oxidative stress is also considered a main component of …

Skeletal muscle is composed of heterogeneous populations of myofibers that are classified
as slow-and fast-twitch fibers. The muscle fiber-type is regulated in a coordinated fashion by …